Suppr超能文献

成人烧伤手术期间失血量的估计。

Estimation of blood loss during adult burn surgery.

作者信息

Farny B, Fontaine M, Latarjet J, Poupelin J C, Voulliaume D, Ravat F

机构信息

Burn Intensive Care Unit, Saint Joseph Saint Luc Hospital, 20 quai Claude Bernard, 69007 Lyon, France.

Burn Intensive Care Unit, Saint Joseph Saint Luc Hospital, 20 quai Claude Bernard, 69007 Lyon, France.

出版信息

Burns. 2018 Sep;44(6):1496-1501. doi: 10.1016/j.burns.2018.04.019. Epub 2018 May 22.

Abstract

INTRODUCTION

Large burns excision and graft can produce major blood loss. The main objective of this study is to evaluate the blood loss in relation with the excision size in square centimeters (cm) in adults.

PATIENTS AND METHODS

We conducted a monocentric, observational, prospective and open study in a burn intensive care unit. Patients aged-over 18 with burn wounds excision and autografting covering at least 5% of total body surface area (TBS) were enrolled. Blood loss was evaluated with Mercuriali formula.

RESULTS

139 procedures were evaluated: median graft size was 1637cm, median blood loss was 0.8ml/cm excised and grafted skin and median total blood loss was 1444ml. 84 procedures (i.e. 60.4%) required transfusion. 66 procedures concerned upper limbs, 75 lower limbs, 17 head and 72 trunk. 126 procedures used tangential excision, 10 used fascia excision and 3 used the two techniques. Patients with comorbidities (ASA score 3 or 4) had more bleeding (p=0.001).

CONCLUSION

The results that were obtained, i.e. approximately 0.8ml/cm of excised and grafted skin, are similar to those of other published studies, which concerned specific populations such as pediatrics. Determining blood loss in one centre can help physicians to calculate the excisable area without any transfusion. However, blood loss can vary widely between patients and one must consider individual clinical situation to provide safe surgery.

摘要

引言

大面积烧伤切除与植皮会导致大量失血。本研究的主要目的是评估成人每平方厘米(cm)切除面积相关的失血量。

患者与方法

我们在一家烧伤重症监护病房开展了一项单中心、观察性、前瞻性开放性研究。纳入年龄超过18岁、烧伤创面切除及自体植皮面积至少占全身表面积(TBS)5%的患者。采用Mercuriali公式评估失血量。

结果

共评估了139例手术:植皮面积中位数为1637cm,每切除及移植1平方厘米皮肤的失血量中位数为0.8ml,总失血量中位数为1444ml。84例手术(即60.4%)需要输血。涉及上肢的手术66例,下肢75例,头部17例,躯干72例。126例手术采用削痂切除,10例采用筋膜切除,3例采用两种技术。有合并症(ASA评分3或4)的患者出血更多(p = 0.001)。

结论

本研究得出的结果,即每切除及移植1平方厘米皮肤约失血0.8ml,与其他已发表研究(涉及儿科等特定人群)的结果相似。在一个中心确定失血量有助于医生在不输血的情况下计算可切除面积。然而,患者之间的失血量差异可能很大,必须考虑个体临床情况以确保手术安全。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验