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肝移植外科医生施行的肝硬化患者腹部手术的结果:这些手术安全吗?

Outcomes of abdominal surgeries in cirrhotic patients performed by liver transplant surgeons: Are these safe?

机构信息

Tampa General Medical Group, Tampa General Hospital, 409 Bayshore Blvd, Tampa, FL 33606, USA.

University of South Florida, Muma College of Business, Tampa, FL 33620, USA.

出版信息

Am J Surg. 2018 Sep;216(3):518-523. doi: 10.1016/j.amjsurg.2018.05.006. Epub 2018 May 12.

Abstract

BACKGROUND

Elective abdominal surgeries in patients with cirrhosis have been discouraged due to the high risk of complications. This study investigates the outcomes and safety of surgeries for hernias, and laparoscopic cholecystectomies in cirrhotic patients.

METHODS

A retrospective cohort study that compared 91 cirrhotic patients to a control group of non-cirrhotic patients operated by liver transplant surgeons was conducted between 2009 and 2015.

RESULTS

No statistical significance found in re-admission rates or complication rates (p = 0.21). Hernia recurrent rates were similar (p = 0.27). Survival rates among cirrhotic versus non cirrhotic group was 93.4% and 98.9% respectively (p = 0.0539). Amongst the 91 cirrhotic patients, there was a 100% survival rate for both ventral herniorrhaphies and laparoscopic cholecystectomy. Survival in umbilical and inguinal herniorrhaphies was 88.2% and 89.5% respectively. Mortality rate for umbilical and inguinal hernias was 11.7% and10.5% respectively. Mortality by Child-Pugh (CP) class were; 8.8% for CP B and 10.7% for CP class C. All CP class A patients survived.

CONCLUSIONS

Our study indicates that elective operations could be performed safely with acceptable mortality in cirrhotic patients.

摘要

背景

由于肝硬化患者并发症风险高,以往不建议择期进行腹部手术。本研究旨在探讨肝硬化患者疝修补术和腹腔镜胆囊切除术的结局和安全性。

方法

回顾性队列研究比较了 2009 年至 2015 年间由肝移植外科医生为 91 例肝硬化患者和非肝硬化患者对照组进行的手术。

结果

再入院率或并发症率无统计学差异(p=0.21)。疝复发率相似(p=0.27)。肝硬化组与非肝硬化组的生存率分别为 93.4%和 98.9%(p=0.0539)。在 91 例肝硬化患者中,腹侧疝修补术和腹腔镜胆囊切除术的 100%生存率。脐疝和腹股沟疝的生存率分别为 88.2%和 89.5%。脐疝和腹股沟疝的死亡率分别为 11.7%和 10.5%。按 Child-Pugh(CP)分级的死亡率分别为:CP B 级为 8.8%,CP C 级为 10.7%。所有 CP A 级患者均存活。

结论

我们的研究表明,择期手术在肝硬化患者中是安全的,死亡率可接受。

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