Hui M, Xu Y, Zhang N, He X D, Qu Q
Department of General Surgery, Peking Union Medical College Hospital, Beijing 100730, China.
Zhonghua Yi Xue Za Zhi. 2018 May 15;98(18):1439-1442. doi: 10.3760/cma.j.issn.0376-2491.2018.18.014.
To summarize the clinical manifestations, pathological features, diagnosis, and treatment of abdominal solitary fibrous tumor (SFT). The data of clinical manifestations, pathological features, diagnosis, and treatment of 18 patients with abdominal SFT admitted to Department of General Surgery, Peking Union Medical College Hospital between January 2000 and December 2016 were retrospectively reviewed. Abdominal mass was first presented in 14 patients. The blood routine, liver, kidney, and coagulation function were normal in all the patients. Tumor markers were abnormal in 4 cases. Most SFT showed hypoechoic mass with regular shape under ultrasound. CT findings differed among the cases. All the 18 patients underwent surgical treatment, and the diagnosis was proved by the postoperative histopathology. SFT differed in general morphology. The positive rate of Ki-67, smooth muscle actin (SMA), CD34, and S-100 was high under immunohistochemistry. Early diagnosis of abdominal SFT is difficult, leading to a low preoperative diagnosis rate. Complete removal of the tumor is the only reliable method of radical treatment.
总结腹部孤立性纤维性肿瘤(SFT)的临床表现、病理特征、诊断及治疗方法。回顾性分析2000年1月至2016年12月期间北京协和医院普通外科收治的18例腹部SFT患者的临床表现、病理特征、诊断及治疗资料。14例患者首发症状为腹部肿块。所有患者血常规、肝肾功能及凝血功能均正常。4例患者肿瘤标志物异常。多数SFT在超声下表现为形态规则的低回声肿块。CT表现各病例不同。18例患者均接受手术治疗,术后病理证实诊断。SFT大体形态各异。免疫组化显示Ki-67、平滑肌肌动蛋白(SMA)、CD34及S-100阳性率较高。腹部SFT早期诊断困难,术前诊断率较低。完整切除肿瘤是唯一可靠的根治方法。