Tabata Nobuko, Nagano Inoue Chiyoko
Department of Dermatology, Japanese Red Cross Sendai Hospital, Taihaku-ku, Sendai, Japan.
Department of Pediatrics, Japanese Red Cross Sendai Hospital, Taihaku-ku, Sendai, Japan.
Case Rep Dermatol. 2018 Apr 24;10(1):89-95. doi: 10.1159/000488901. eCollection 2018 Jan-Apr.
We report a 10-year-old boy with localized scleroderma of the linear and plaque type, who showed proteinuria and hematuria. In this patient, skin, articular, and renal manifestations appeared successively and then began to resolve in the same order. A renal biopsy specimen demonstrated mild mesangial cell proliferation, exudate of immunoglobulin in the glomerular capillary, and large electron-dense deposits in the afferent arteriole. We consider that there were some transient factors that had caused the skin and articular manifestations, which also induced renal vascular inflammatory responses.
我们报告一名10岁患有线性和斑块型局限性硬皮病的男孩，其出现蛋白尿和血尿。在该患者中，皮肤、关节和肾脏表现相继出现，然后又按相同顺序开始消退。肾活检标本显示轻度系膜细胞增生、肾小球毛细血管内免疫球蛋白渗出以及入球小动脉中有大量电子致密沉积物。我们认为存在一些导致皮肤和关节表现的短暂因素，这些因素也诱发了肾血管炎症反应。
