School of Biological Sciences, Illinois State University, Normal, Illinois.
J Exp Zool A Ecol Integr Physiol. 2018 Apr;329(4-5):177-184. doi: 10.1002/jez.2183. Epub 2018 May 28.
Vertebrates with temperature-dependent sex determination (TSD) have justifiably received a lot of attention when it comes to the potential effects of climate change. Freshwater turtles have long been used to characterize the physiological and genetic mechanisms underlying TSD and provide a great system to investigate how changing climatic conditions will affect vertebrates with TSD. Unfortunately, most of what we know about the mechanisms underlying TSD comes from laboratory conditions that do not accurately mimic natural conditions (i.e., constant incubation temperatures and supraphysiological steroid manipulations). In this paper, we review recent advances in our understanding of how TSD operates in nature that arose from studies using more natural fluctuating incubation temperatures and natural variation in maternal estrogens within the yolk. By incorporating more natural conditions into laboratory studies, we are better able to use these studies to predict how changing climatic conditions will affect species with TSD.
具有温度依赖型性别决定（TSD）的脊椎动物在气候变化的潜在影响方面引起了广泛关注。淡水龟长期以来一直被用于描述 TSD 的生理和遗传机制，并为研究气候变化条件将如何影响具有 TSD 的脊椎动物提供了一个很好的系统。不幸的是，我们对 TSD 潜在机制的了解大多来自于实验室条件，这些条件并不能准确模拟自然条件（即，恒定的孵化温度和超生理类固醇处理）。在本文中，我们回顾了最近在使用更自然的波动孵化温度和蛋黄中母体雌激素的自然变异来研究 TSD 在自然界中如何运作方面的进展。通过将更多的自然条件纳入实验室研究，我们能够更好地利用这些研究来预测气候变化条件将如何影响具有 TSD 的物种。
