Adams Daniel L, Rapone Brittany C, Economides John R, Horton Jonathan C
J Pediatr Ophthalmol Strabismus. 2018 Sep 20;55(5):335-338. doi: 10.3928/01913913-20180328-01. Epub 2018 May 29.
To assess the outcome of free tenotomy of the medial rectus muscle in post-natal monkeys.
The medial rectus muscle was disinserted in both eyes of 6 macaques at age 4 weeks to induce an alternating exotropia. After the impact on the visual cortex and superior colliculus was investigated, the animals were examined post-mortem to assess the anatomy of the medial rectus muscles.
After tenotomy, the monkeys eventually recovered partial adduction. Necropsy revealed that all 12 medial rectus muscles had reattached to the globe. They were firmly connected via an abnormally long tendon, but at the native insertion site.
Medial rectus muscles are able to reattach spontaneously to the eye following free tenotomy in post-natal macaques. The early timing of surgery and the large size of the globe relative to the orbit may explain why reinsertion occurs more readily in monkeys than in children with a lost muscle after strabismus surgery. [J Pediatr Ophthalmol Strabismus. 2018;55(5):335-338.].
评估出生后猴子内直肌游离腱切断术的效果。
在6只4周龄猕猴的双眼行内直肌断腱术以诱发交替性外斜视。在研究对视皮层和上丘的影响后,对动物进行尸检以评估内直肌的解剖结构。
腱切断术后,猴子最终恢复了部分内收功能。尸检显示,所有12条内直肌均重新附着于眼球。它们通过异常长的肌腱牢固连接,但附着于原附着部位。
出生后的猕猴在内直肌游离腱切断术后,内直肌能够自发地重新附着于眼球。手术时机早以及相对于眼眶而言眼球较大,可能解释了为什么猴子比斜视手术后肌肉缺失的儿童更容易发生重新附着。[《小儿眼科与斜视杂志》。2018;55(5):335 - 338。]