van der Woude F J, van Son W J, Tegzess A M, Donker A J, Slooff M J, van der Slikke L B, Hoorntje S J
Nephron. 1985;39(3):184-8. doi: 10.1159/000183369.
We evaluated 9 patients with transplant renal artery stenosis. Captopril treatment always resulted in a dramatic decrease in renal function. Moreover, only in patients (n = 2) with a stenosis in one out of more renal arteries a satisfying fall in blood pressure was achieved. Surgical reconstruction of the stenosis was successful in 4 out of 5 patients. Angiotensin I-converting enzyme inhibition in transplant renal artery stenosis often leads to loss of graft function, probably due to efferent vasodilation.
我们评估了9例移植肾动脉狭窄患者。卡托普利治疗总是导致肾功能急剧下降。此外,仅在1条或多条肾动脉中有狭窄的患者(n = 2)中,血压出现了令人满意的下降。5例患者中有4例狭窄的外科重建手术成功。移植肾动脉狭窄时使用血管紧张素I转换酶抑制剂常导致移植肾功能丧失,可能是由于出球小动脉扩张所致。