Sacquet E, Leprince C, Riottot M, Raibaud P
Reprod Nutr Dev (1980). 1985;25(1A):93-100. doi: 10.1051/rnd:19850109.
Axenic (germfree) and holoxenic (conventional) rats were given a pectin-containing diet (5%) or a pectin-free diet. The diet was not sterilized and the axenic state was maintained by the addition of antibiotics. Pectin modified little or not at all the quantity of bile acids in the small intestine, fecal bile acid excretion and fecal elimination of the sum of cholesterol and bile acids. It similarly decreased the concentration of liver cholesterol and the amount of bile acids in the cecum and large intestine of both germfree and conventional rats. Pectin decreased the absorption coefficient of dietary cholesterol and its plasma concentration and increased fecal cholesterol elimination in conventional rats but not in germfree animals. The data imply that some of the actions of pectin depend on the presence of the intestinal flora but the exact nature of this relationship is unclear.
将无菌（无特定病原体）和普通（常规）大鼠分别给予含果胶饮食（5%）或不含果胶饮食。饮食未进行灭菌处理，无菌状态通过添加抗生素维持。果胶对小肠中胆汁酸的量、粪便胆汁酸排泄以及胆固醇和胆汁酸总和的粪便消除影响很小或几乎没有影响。同样，它降低了无菌和普通大鼠肝脏胆固醇浓度以及盲肠和大肠中胆汁酸的量。果胶降低了普通大鼠饮食胆固醇的吸收系数及其血浆浓度，并增加了粪便胆固醇的消除，但在无菌动物中没有这种作用。数据表明，果胶的某些作用取决于肠道菌群的存在，但这种关系的确切性质尚不清楚。
