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[训练有素的运动员静息及分级体育锻炼时的游离和结合血浆儿茶酚胺、乳酸变化及摄氧量以及完整血小板中的α受体密度]

[Free and conjugated plasma catecholamines, lactate behavior and oxygen uptake at rest and in staged physical exertion as well as alpha receptor density in intact thrombocytes in trained athletes].

作者信息

Lehmann M, Jakob E, Spöri U, Bergdolt E, Keul J

出版信息

Z Kardiol. 1985 Jan;74(1):32-8.

PMID:2983504
Abstract

The influence of chronic static training on free and conjugated plasma catecholamines was investigated in 8 statically trained athletes (21 +/- 2 years of age) at rest and during incremental ergometric cycling. Plasma catecholamines are seen as biochemical indicators of the over-all sympathetic activity. Alpha-2-adrenoreceptors were additionally determined as one parameter of the organism's sensitivity to catecholamines. During modest and heavy exercise, free plasma noradrenaline and adrenaline are comparably low in statically and endurance trained athletes. They are lower than in untrained subjects. During exhaustion, however, free adrenaline responses of the statically trained athletes only amount to 30-50% of the concentrations observed in endurance trained athletes and untrained subjects. Free plasma dopamine and conjugated plasma catecholamines do not show any significant changes during ergometric exercise. Free and conjugated catecholamines correlate positively. Positive correlations are also observed between blood pressure and plasma catecholamines. These correlations however are clearer between conjugated catecholamines and blood pressure. This is also recognizable for the negative correlation between alpha-2-receptor density on intact platelets (1078 +/- 323 binding sites per cell) and conjugated catecholamines. In conclusion, statically trained athletes also show an alteration of sympathetic tone (catecholamines) comparable to that observed in endurance trained athletes. Maximal adrenaline responses however are lower in statically trained athletes than in endurance trained or untrained subjects. The alpha-adrenoreceptor density on intact thrombocytes seems to be increased in statically trained athletes.

摘要

对8名进行静力训练的运动员(年龄21±2岁)在静息状态和递增运动负荷的测力计骑行过程中,研究了慢性静力训练对游离和结合型血浆儿茶酚胺的影响。血浆儿茶酚胺被视为整体交感神经活动的生化指标。另外,将α-2-肾上腺素能受体作为机体对儿茶酚胺敏感性的一个参数进行测定。在适度和剧烈运动期间,进行静力训练和耐力训练的运动员的游离血浆去甲肾上腺素和肾上腺素水平相对较低。它们低于未训练的受试者。然而,在力竭时,进行静力训练的运动员的游离肾上腺素反应仅为耐力训练的运动员和未训练受试者中观察到的浓度的30%-50%。在测力计运动期间,游离血浆多巴胺和结合型血浆儿茶酚胺没有显示出任何显著变化。游离和结合型儿茶酚胺呈正相关。血压与血浆儿茶酚胺之间也观察到正相关。然而,结合型儿茶酚胺与血压之间的这些相关性更明显。完整血小板上的α-2-受体密度(每个细胞1078±323个结合位点)与结合型儿茶酚胺之间的负相关也很明显。总之,进行静力训练的运动员也表现出与耐力训练的运动员中观察到的交感神经张力(儿茶酚胺)变化相当。然而,进行静力训练的运动员的最大肾上腺素反应低于耐力训练的运动员或未训练的受试者。在进行静力训练的运动员中,完整血小板上的α-肾上腺素能受体密度似乎增加。

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