Barkov N K, Machula A I
Farmakol Toksikol. 1985 Jan-Feb;48(1):20-3.
It has been shown on cats with the method of the conditional defensive reflexes and parallel recording of the bioelectric activity that the serotonin-negative and dopamine-positive substances restore the similarity of the amplitude-temporary parameters of evoked potentials in the visual, associative and the second comatosencory fields of the brain cortex, disturbed by delta-9-tetrahydrocannabinol injection. It has been also demonstrated that the serotoninergic substances influence the action of delta-9-tetrahydrocannabinol both on the early and late waves of evoked potentials whereas the dopaminergic substances influence the drug action only on the late waves.
采用条件防御反射方法并同时记录生物电活动，对猫进行实验，结果表明，5-羟色胺阴性和多巴胺阳性物质可恢复被注射δ-9-四氢大麻酚干扰的大脑皮层视觉、联合及第二躯体感觉区诱发电位的波幅-时间参数的相似性。还证实，5-羟色胺能物质对δ-9-四氢大麻酚在诱发电位早期和晚期波上的作用均有影响，而多巴胺能物质仅对药物在晚期波上的作用有影响。
