Lesec G, Gogusev J, Fermaud H, Gorce D, Lemaitre J P, Verdier A
Gastroenterol Clin Biol. 1985 Feb;9(2):166-8.
A case of esophageal Papilloma is reported. The viral condyloma was diagnosed by standard histological methods and confirmed by immuno-fluorescence and immuno-peroxidase technics against genus specific Papilloma virus antigens (i. e. capsid specific proteic antigen). These antigens were localized in the nuclei of koilocytic cells. These results confirm the association between proliferative lesions appearing on the mucosal epithelium and Papilloma viruses, which are suspected to be oncogenic in other malpighian tissues.
报告了一例食管乳头状瘤病例。通过标准组织学方法诊断为病毒性湿疣,并通过针对属特异性乳头瘤病毒抗原(即衣壳特异性蛋白抗原)的免疫荧光和免疫过氧化物酶技术进行了确认。这些抗原定位于空泡化细胞的细胞核中。这些结果证实了黏膜上皮出现的增殖性病变与乳头瘤病毒之间的关联,而乳头瘤病毒在其他马尔皮基组织中被怀疑具有致癌性。