Masfari A N, Kinghorn G R, Hafiz S, Barton I G, Duerden B I
Genitourin Med. 1985 Apr;61(2):109-13. doi: 10.1136/sti.61.2.109.
Of 91 patients with genital ulceration, herpes simplex virus was isolated from 52 (57%) and Haemophilus ducreyi from 12 (13%); none had syphilis. The difference in incidence of other aerobes in patients and controls was not significant. Anaerobes, predominantly Bacteroides spp, were isolated from a large proportion (77%) of men and women patients with ulcers but from few control men. The most common anaerobic species were B asaccharolyticus and B ureolyticus, with fewer isolates of the melaninogenicus/oralis group. The bacterial flora of herpetic and non-herpetic ulcers were similar, but Candida albicans was isolated significantly more often from non-herpetic ulcers. Anaerobic bacteria may contribute to the pathogenesis of genital ulcers.
在91例生殖器溃疡患者中，从52例（57%）分离出单纯疱疹病毒，从12例（13%）分离出杜克雷嗜血杆菌；无人患有梅毒。患者和对照组中其他需氧菌的发病率差异不显著。厌氧菌，主要是拟杆菌属，从很大比例（77%）的男性和女性溃疡患者中分离出来，但很少从对照男性中分离出来。最常见的厌氧菌种是解糖拟杆菌和解脲拟杆菌，产黑色素/口腔菌群的分离株较少。疱疹性溃疡和非疱疹性溃疡的细菌菌群相似，但白色念珠菌在非疱疹性溃疡中分离出的频率明显更高。厌氧菌可能在生殖器溃疡的发病机制中起作用。
