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短期椎间盘表观弥散度增加与腰痛脊柱活动后疼痛和活动度改善相关。

Short-term increase in discs' apparent diffusion is associated with pain and mobility improvements after spinal mobilization for low back pain.

机构信息

OMT Skills, Private physical therapy practice, La Louvière, 7100, Belgium.

Center for Rehabilitation Research and Department of Rehabilitation Sciences, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.

出版信息

Sci Rep. 2018 May 29;8(1):8281. doi: 10.1038/s41598-018-26697-7.

DOI:10.1038/s41598-018-26697-7
PMID:29844484
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5974269/
Abstract

Pain perception, trunk mobility and apparent diffusion coefficient (ADC) within all lumbar intervertebral discs (IVDs) were collected before and shortly after posterior-to-anterior (PA) mobilizations in 16 adults with acute low back pain. Using a pragmatic approach, a trained orthopaedic manual physical therapist applied PA mobilizations to the participants' spine, in accordance with his examination findings. ADC was computed from diffusion maps as the mean of anterior (ADC ), middle (ADC ), and posterior (ADC ) portions of the IVD. After mobilization, pain ratings and trunk mobility were significantly improved and a significant increase in ADC values was observed. The greatest ADC changes were observed at the L-L and L-L levels and were mainly explained by changes in ADC and ADC , respectively. No significant changes in ADC were observed at L-S level. The reduction in pain and largest changes in ADC observed at the periphery of the hyperintense IVD region suggest that increased peripheral random motion of water molecules is implicated in the IVD nociceptive response modulation. Additionally, ADC changes were observed at remote IVD anatomical levels that did not coincide with the PA spinal mobilization application level.

摘要

在 16 名患有急性腰痛的成年人中,在进行前后(PA)推拿前后收集了他们所有腰椎间盘(IVD)的疼痛感知、躯干活动度和表观扩散系数(ADC)。一位经过培训的骨科手法治疗师根据他的检查结果,采用实用的方法对参与者的脊柱进行了 PA 推拿。ADC 是通过扩散图谱计算出来的,是 IVD 前(ADC )、中(ADC )和后(ADC )部分的平均值。推拿后,疼痛评分和躯干活动度显著改善,ADC 值显著增加。在 L-L 和 L-L 水平观察到最大的 ADC 变化,这主要归因于 ADC 和 ADC 的变化。在 L-S 水平没有观察到 ADC 的显著变化。在高信号 IVD 区域的外围观察到疼痛减轻和 ADC 最大变化,这表明水分子的外围随机运动增加与 IVD 伤害感受反应调节有关。此外,在与 PA 脊柱推拿应用水平不重合的远程 IVD 解剖水平观察到 ADC 变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50c/5974269/22073ae947a8/41598_2018_26697_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50c/5974269/15694a81870b/41598_2018_26697_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50c/5974269/fb9ee304d9f5/41598_2018_26697_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50c/5974269/b96be5c0e124/41598_2018_26697_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50c/5974269/e5b46ffb019f/41598_2018_26697_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50c/5974269/f03c76842dbb/41598_2018_26697_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50c/5974269/22073ae947a8/41598_2018_26697_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50c/5974269/15694a81870b/41598_2018_26697_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50c/5974269/fb9ee304d9f5/41598_2018_26697_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50c/5974269/b96be5c0e124/41598_2018_26697_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50c/5974269/e5b46ffb019f/41598_2018_26697_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50c/5974269/f03c76842dbb/41598_2018_26697_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50c/5974269/22073ae947a8/41598_2018_26697_Fig6_HTML.jpg

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本文引用的文献

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