Wang Zhiliang, Lu Jiali, Li Qingwei, Pang Yue
College of Life Science, Liaoning Normal University, Dalian 116081, China.
Lamprey Research Center, Liaoning Normal University, Dalian 116081, China.
Data Brief. 2018 Feb 15;17:1271-1275. doi: 10.1016/j.dib.2018.02.036. eCollection 2018 Apr.
The data presented in this article are related to the research article entitled "Characterization of the LECT2 gene and its protective effects against microbial infection via large lymphocytes in " (Wang et al., 2017) [1]. Here, we presented new original data about the effect of rL-LECT2 on cancer cells migration and macrophages phagocytosis. Wound healing assay and transwell chemotaxis assays were used to measure rL-LECT2 inhibition rates on cancer cell migration. Additionally, fluospheres beads and FITC were used to measure whether the rL-LECT2 can affect the phagocytosis of RAW264.7 cells.
本文所呈现的数据与题为《LECT2基因的特征及其通过大淋巴细胞对微生物感染的保护作用》(Wang等人,2017年)[1]的研究论文相关。在此,我们展示了关于重组人LECT2(rL-LECT2)对癌细胞迁移和巨噬细胞吞噬作用影响的新的原始数据。采用伤口愈合试验和Transwell趋化试验来测量rL-LECT2对癌细胞迁移的抑制率。此外,使用荧光微球珠和异硫氰酸荧光素(FITC)来检测rL-LECT2是否能影响RAW264.7细胞的吞噬作用。