Institute of Resource Ecology, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstr. 400, 01328 Dresden, Germany.
Chem Commun (Camb). 2018 Aug 2;54(63):8697-8700. doi: 10.1039/c8cc02070a.
Glutathione (GSH), a ubiquitous intracellular reducing tripeptide, is able to reduce hexavalent uranium, U(vi), to its tetravalent form, U(iv), in aqueous media in vitro, inducing the formation of nanocrystalline mixed-valence uranium oxide particles. After the initial reduction to U(v) and subsequent dismutation, the yielded U(iv) rapidly hydrolyses under near-neutral conditions forming 2-5 nm sized nanoparticles. The latter further aggregate to 20-40 nm chain-like building blocks that finally arrange as network-like structures.
谷胱甘肽（GSH）是一种普遍存在于细胞内的三肽还原物质，能够将六价铀（U(vi)）还原成其四价形式（U(iv)），在体外的水介质中诱导纳米晶混合价态氧化铀颗粒的形成。在最初还原为 U(v)并随后歧化后，生成的 U(iv)在近中性条件下迅速水解，形成 2-5nm 大小的纳米颗粒。后者进一步聚集形成 20-40nm 的链状构建块，最终排列成网络状结构。
