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希腊北部一名儿童患伴有明显血小板减少症的鼠型斑疹伤寒及文献综述

Murine Typhus with Marked Thrombocytopenia in a Child in Northern Greece and Literature Review.

作者信息

Sarikloglou Evangelia, Goula Anastasia, Sidiropoulos Charalampos, Tsolia Maria, Papa Anna

机构信息

Pediatric Department of General Hospital of Kavala.

2nd Department of Pediatrics, National and Kapodistrian University of Athens School of Medicine, "P. & A. Kyriakou" Children's Hospital.

出版信息

Jpn J Infect Dis. 2018 Sep 21;71(5):368-369. doi: 10.7883/yoken.JJID.2018.091. Epub 2018 May 31.

Abstract

We report a case of murine typhus in a 4-year-old boy living in northern Greece. Although the illness started with mild symptoms, a maculopapular rash appeared by the end of the first week of illness followed by marked thrombocytopenia. The detection of IgM antibodies against Rickettsia typhi in the patient's blood and a positive polymerase chain reaction result combined with sequencing confirmed the diagnosis of infection by Rickettsia typhi. Clinicians in northern Greece should be aware of the disease, even in cases presenting with no specific initial symptoms.

摘要

我们报告了一例在希腊北部居住的4岁男孩感染鼠型斑疹伤寒的病例。尽管疾病起初症状较轻,但在发病第一周结束时出现了斑丘疹,随后出现明显的血小板减少。在患者血液中检测到抗伤寒立克次体的IgM抗体,聚合酶链反应结果呈阳性并结合测序,证实了伤寒立克次体感染的诊断。希腊北部的临床医生应了解这种疾病,即使是在没有特定初始症状的病例中。

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