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剖宫产术后子宫瘢痕部位妊娠:当前的管理策略。

Cesarean Scar Ectopic Pregnancy: Current Management Strategies.

机构信息

Obstetrics and Gynecology Resident, Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Boonshoft School of Medicine, Wright State University, Dayton, OH; Obstetrics and Gynecology Resident, Department of Obstetrics and Gynecology, Wright-Patterson Medical Center, Wright-Patterson Air Force Base.

Assistant Clinical Professor of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Boonshoft School of Medicine, Wright State University, Dayton, OH.

出版信息

Obstet Gynecol Surv. 2018 May;73(5):293-302. doi: 10.1097/OGX.0000000000000561.

Abstract

IMPORTANCE

Cesarean scar ectopic pregnancy (CSEP) has a high rate of morbidity with nonspecific signs and symptoms making identification difficult. The criterion-standard treatment of CSEP has been subject to debate.

OBJECTIVE

This review defines CSEP, discusses pathogenesis and diagnosis, and compares treatment options and outcomes.

EVIDENCE ACQUISITION

A literature review was performed utilizing the term and subsequently selecting only meta-analyses and systematic reviews. Only articles published in English were included. Relevant articles within the reviews were analyzed as necessary.

RESULTS

Five basic pathways have been identified in treatment of CSEP: expectant management, medical therapy, surgical intervention, uterine artery embolization, or a combination approach. Expectant management has the highest probability of morbid outcomes, including hemorrhage, uterine rupture, and preterm delivery. Medical management often requires further treatment with additional medication or surgery. Different surgical methods have been explored including uterine artery embolization; dilation and curettage; surgical removal via vaginal, laparoscopic, or laparotomic approach; and hysterectomy. Each method has various levels of success and depends on surgeon skill and patient presentation.

CONCLUSIONS

Recent research supports any method that removes the pregnancy and scar to reduce morbidity and promote future fertility. Laparoscopic and transvaginal approaches are options for CSEP treatment, although continued research is required to identify the optimal approach.

RELEVANCE

As cesarean delivery numbers rise, a subsequent increase in CSEPs can be anticipated. The ability to accurately diagnose and treat this morbid condition is vital to the practice of any specialist in general obstetrics and gynecology.

摘要

重要性

剖宫产瘢痕部位妊娠(CSEP)发病率高,且具有非特异性的体征和症状,导致诊断困难。CSEP 的标准治疗方法一直存在争议。

目的

本文对 CSEP 的定义、发病机制和诊断进行了讨论,并对治疗选择和结局进行了比较。

证据获取

通过使用术语“Cesarean scar ectopic pregnancy”进行文献检索,随后仅选择荟萃分析和系统评价。仅纳入发表于英文期刊的文章。对综述中的相关文章进行了必要的分析。

结果

已确定 CSEP 的五种基本治疗途径:期待治疗、药物治疗、手术干预、子宫动脉栓塞治疗或联合治疗。期待治疗发生不良结局的可能性最高,包括出血、子宫破裂和早产。药物治疗通常需要进一步使用其他药物或手术治疗。已经探索了不同的手术方法,包括子宫动脉栓塞术、扩张刮宫术、经阴道、腹腔镜或剖腹手术切除以及子宫切除术。每种方法的成功率不同,取决于外科医生的技能和患者的具体情况。

结论

最近的研究支持任何一种可以移除妊娠物和瘢痕组织的方法,以降低发病率并促进未来生育能力。腹腔镜和经阴道方法是 CSEP 治疗的选择,尽管需要进一步研究以确定最佳方法。

相关性

随着剖宫产分娩数量的增加,CSEP 的数量预计会随之增加。准确诊断和治疗这种严重疾病对于普通妇产科专家的实践至关重要。

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