用自旋标记法研究硬化红细胞的存在对正常红细胞在剪切流中变形取向特性的影响。
Effect of the presence of hardened erythrocytes on deformation-orientation characteristics of normal erythrocytes in shear flow studied by the spin label method.
作者信息
Kon K, O'Bryan E R, Kon H
出版信息
Biorheology. 1985;22(2):105-17. doi: 10.3233/bir-1985-22202.
The effect of the presence of hardened red blood cells (HRBC) in a mixed suspension on the deformation-orientation characteristics of normal cells in flow is experimentally probed by the electron spin resonance (ESR) spin label method, using a phosphatidylcholine label which does not transfer between the cells. The average deformation-orientation of the normal cells is generally suppressed by the presence of HRBC to different degrees, depending upon the shape and the way the HRBC are prepared. The effects are qualitatively explained by disturbance of laminar shear flow due to the random tumbling of the HRBC.
通过电子自旋共振（ESR）自旋标记法，使用一种不会在细胞间转移的磷脂酰胆碱标记物，对混合悬浮液中硬化红细胞（HRBC）的存在对流动中正常细胞变形取向特性的影响进行了实验探究。正常细胞的平均变形取向通常会因HRBC的存在而受到不同程度的抑制，这取决于HRBC的形状和制备方式。这些影响可以通过HRBC的随机翻滚对层流剪切流的干扰进行定性解释。
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