Sturgill Emily L, Wittwer Robert L
From the Wright-Patterson Medical Center, Wright-Patterson Air Force Base, Ohio.
A A Pract. 2018 Jul 1;11(1):25-27. doi: 10.1213/XAA.0000000000000801.
Patients with upper motor neuron disease, such as multiple sclerosis, can present with severe spasticity in the perioperative period. In most cases, this can be managed with a combination of preoperative oral medications, regional or neuraxial anesthetic techniques, and intravenous muscle relaxants. We describe the clinical presentation of a patient with multiple sclerosis and the successful use of intravenous dantrolene sodium postoperatively for the treatment of exacerbated spasticity refractory to traditional management.
上运动神经元疾病患者，如多发性硬化症患者，在围手术期可能出现严重痉挛。在大多数情况下，这可以通过术前口服药物、区域或神经轴麻技术以及静脉肌肉松弛剂联合治疗。我们描述了一名多发性硬化症患者的临床表现，以及术后成功使用静脉注射丹曲林钠治疗传统治疗方法难以控制的痉挛加重情况。
