Institute of Chronic and Non-communicable Disease Control and Prevention, Hubei Provincial Center for Disease Control and Prevention, Hubei, China.
Department of Respiratory Medicine, The Third People's Hospital of Hubei Province, Hubei, China.
Public Health. 2018 Aug;161:12-19. doi: 10.1016/j.puhe.2018.02.016. Epub 2018 May 28.
The trends of chronic obstructive pulmonary disease (COPD) mortality and prevalence from 1990 to 2015 in Hubei province of mid-China remain unknown. We used findings from the Global Burden of Disease (GBD) 2015 study to estimate the COPD burden and attributable to risk factors in Hubei province of China from 1990 to 2015.
The GBD study uses various analytical tools and a diverse set of data sources to generate comparable estimates of deaths and mortality rates broken down by age, sex, cause, year, and geography.
Data were extracted from the GBD 2015 study. Statistical models were used to produce comprehensive results of COPD deaths, prevalence, disability-adjusted life years (DALYs), years of life lost, years lived with a disability, and attributable to risk factors in Hubei. The median of the percent change and 95% uncertainty intervals were determined for the period between 1990 and 2015.
In 2015, there were 37,144 deaths from COPD in Hubei, accounting for 10.05% of the total deaths in Hubei. The age-standardized COPD death rate was reduced by 60.28% from 188.67 per 100,000 (in 1990) to 74.94 per 100,000 (in 2015). The age-standardized prevalence decreased from 4.30% (1990) to 2.85% (2015). By 2015, the leading risk factors for all ages COPD DALYs were smoking and ambient particulate matter pollution, accounting for 44.69% and 32.91%, respectively. The proportion of ambient ozone pollution was increasing steadily each year since 1990.
Hubei has made substantial progress in reducing the mortality due to COPD since 1990, but the absolute number of COPD cases is increasing steadily, given the population growth and aging. The increasing contribution from smoking, ambient particulate matter pollution, and ambient ozone pollution should require growing attention.
目前尚不清楚中国中部湖北省 1990 年至 2015 年期间慢性阻塞性肺疾病（COPD）死亡率和流行率的趋势。我们利用 2015 年全球疾病负担（GBD）研究的结果，估算了 1990 年至 2015 年期间中国湖北省 COPD 的疾病负担以及归因于危险因素的情况。
GBD 研究使用各种分析工具和多样化的数据源，生成按年龄、性别、病因、年份和地理位置划分的死亡率和死亡率的可比估计值。
数据取自 GBD 2015 研究。使用统计模型生成 COPD 死亡、流行率、伤残调整生命年（DALY）、寿命损失年、残疾生存年以及归因于危险因素的综合结果。1990 年至 2015 年期间的百分比变化中位数和 95%置信区间。
2015 年，湖北省有 37144 例 COPD 死亡，占湖北省总死亡人数的 10.05%。年龄标准化 COPD 死亡率从 1990 年的每 10 万人 188.67 例下降到 2015 年的每 10 万人 74.94 例，下降了 60.28%。年龄标准化患病率从 1990 年的 4.30%下降到 2015 年的 2.85%。到 2015 年，所有年龄段 COPD 的主要危险因素是吸烟和环境颗粒物污染，分别占 44.69%和 32.91%。自 1990 年以来，环境臭氧污染的比例每年都在稳步增加。
自 1990 年以来，湖北省在降低 COPD 死亡率方面取得了重大进展，但考虑到人口增长和老龄化，COPD 病例的绝对数量仍在稳步增加。吸烟、环境颗粒物污染和环境臭氧污染的贡献不断增加，应引起越来越多的关注。
