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[毛细支气管炎临床实践指南的多模式实施:终结诊断资源的过度使用]

[Multimodal implementation of clinical practice guidelines on bronchiolitis: ending the overuse of diagnostic resources].

作者信息

Maraña Pérez Ana Isabel, Rius Peris Juan Manuel, Rivas Juesas Cristina, Torrecilla Cañas Javier, Hernández Muelas Sara, de la Osa Langreo Alberto

机构信息

Servicio de Pediatría, Hospital Virgen de la Luz, Cuenca, España.

Servicio de Pediatría, Hospital Virgen de la Luz, Cuenca, España.

出版信息

An Pediatr (Engl Ed). 2018 Dec;89(6):352-360. doi: 10.1016/j.anpedi.2018.02.008. Epub 2018 May 28.

Abstract

INTRODUCTION

Clinical Practice Guidelines have been shown to be valuable tools for guiding medical decisions. However, their mere publication has not reduced the variability of practice in terms of the way acute bronchiolitis is managed.

METHOD

A before-and-after study design was used to analyse the effectiveness of a method of disseminating diagnostic recommendations among physicians regarding the management of infants, hospitalised due to bronchiolitis. Patients with comorbidities, ex-premature patients, and patients transferred to other hospitals were excluded. The diagnostic resources studied were: chest X-ray, full blood count, C-reactive protein, blood culture, venous blood gas, and determination of the respiratory syncytial virus. Eleven epidemic periods were analysed.

RESULTS

A total of 259 patients were studied including 98 in the pre-intervention group (2006-2010), and 131 in the post-intervention group (2011-2017). The intervention took place in October of 2010 and 2011. A comparison of the two periods showed that the use of chest X-rays dropped from 73.5% to 16% (p<.01), full blood counts from 51% to 21.4% (p<.01), C-reactive protein from 48% to 22.1% (p<.01), and blood cultures from 23.5% to 7.6% (p<.01). Length of stay dropped by 0.6 (SD: 1) days and there were no differences in re-admission rates.

CONCLUSIONS

The organised and systematised dissemination, using a multimodal method, of the diagnostic recommendations contained in the clinical practice guidelines on bronchiolitis, is capable of transforming the clinical practice by reducing the use of diagnostic resources, without an increase in the re-admission rate.

摘要

引言

临床实践指南已被证明是指导医疗决策的宝贵工具。然而,就急性细支气管炎的管理方式而言,仅仅发布这些指南并未减少实践中的变异性。

方法

采用前后对照研究设计,分析向医生传播有关因细支气管炎住院婴儿管理的诊断建议方法的有效性。排除患有合并症的患者、早产患者以及转至其他医院的患者。所研究的诊断资源包括:胸部X光、全血细胞计数、C反应蛋白、血培养、静脉血气分析以及呼吸道合胞病毒检测。分析了11个流行期。

结果

共研究了259例患者,其中干预前组98例(2006 - 2010年),干预后组131例(2011 - 2017年)。干预分别于2010年10月和2011年10月进行。两个时期的比较显示,胸部X光检查的使用率从73.5%降至16%(p <.01),全血细胞计数从51%降至21.4%(p <.01),C反应蛋白从48%降至22.1%(p <.01),血培养从23.5%降至7.6%(p <.01)。住院时间缩短了0.6(标准差:1)天,再入院率无差异。

结论

采用多模式方法有组织、系统地传播细支气管炎临床实践指南中的诊断建议,能够通过减少诊断资源的使用来改变临床实践,且不会增加再入院率。

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