太平洋盲鳗（Eptatretus stouti）垂体和大脑中的促肾上腺皮质激素样生物活性。
Corticotrophin-like bioactivity in the pituitary gland and brain of the pacific hagfish, Eptatretus stouti.
作者信息
Buckingham J C, Leach J H, Plisetskaya E, Sower S A, Gorbman A
出版信息
Gen Comp Endocrinol. 1985 Mar;57(3):434-7. doi: 10.1016/0016-6480(85)90225-4.
The cytochemical bioassay for corticotrophin (ACTH) was used in an attempt to detect ACTH-like activity in the Pacific hagfish, Eptatretus stouti. Extracts of the pituitary gland and brain were active in this assay system but those of liver and skeletal muscles were not. The slopes of the dose-response lines of the pituitary extracts were less than those of the mammalian corticotrophin standard preparation but greater than those of the brain extracts. The results suggest that the corticotrophic factor in the hagfish differs from mammalian ACTH.
利用促肾上腺皮质激素（ACTH）的细胞化学生物测定法来检测太平洋盲鳗（Eptatretus stouti）中类似ACTH的活性。垂体和脑的提取物在该测定系统中具有活性，但肝脏和骨骼肌的提取物则没有。垂体提取物的剂量反应线斜率小于哺乳动物促肾上腺皮质激素标准制剂的斜率，但大于脑提取物的斜率。结果表明，盲鳗中的促肾上腺皮质激素因子与哺乳动物的ACTH不同。
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