The Hippo pathway and cancer immunity: friend or foe?
作者信息
Janse van Rensburg Helena J, Yang Xiaolong
机构信息
Department of Pathology and Molecular Medicine, Queen's University, Kingston, Ontario, Canada K7L 3N6.
出版信息
Oncoscience. 2018 Apr 29;5(3-4):49-50. doi: 10.18632/oncoscience.398. eCollection 2018 Mar.
Abstract
摘要
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Oncoscience. 2018 Apr 29;5(3-4):49-50. doi: 10.18632/oncoscience.398. eCollection 2018 Mar.
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本文引用的文献
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YAP regulates PD-L1 expression in human NSCLC cells.YAP调节人非小细胞肺癌细胞中PD-L1的表达。
Oncotarget. 2017 Dec 9;8(70):114576-114587. doi: 10.18632/oncotarget.23051. eCollection 2017 Dec 29.
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The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1.Hippo 通路组件 TAZ 通过 PD-L1 促进人类癌症中的免疫逃避。
Cancer Res. 2018 Mar 15;78(6):1457-1470. doi: 10.1158/0008-5472.CAN-17-3139. Epub 2018 Jan 16.
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Hippo effector YAP directly regulates the expression of PD-L1 transcripts in EGFR-TKI-resistant lung adenocarcinoma.河马效应器YAP直接调控表皮生长因子受体-酪氨酸激酶抑制剂（EGFR-TKI）耐药性肺腺癌中程序性死亡受体配体1（PD-L1）转录本的表达。
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Tumor cell-derived lactate induces TAZ-dependent upregulation of PD-L1 through GPR81 in human lung cancer cells.肿瘤细胞衍生的乳酸通过 GPR81 在人肺癌细胞中诱导 TAZ 依赖性 PD-L1 的上调。
Oncogene. 2017 Oct 19;36(42):5829-5839. doi: 10.1038/onc.2017.188. Epub 2017 Jun 12.
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The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.河马通路激酶LATS1/2抑制癌症免疫。
Cell. 2016 Dec 1;167(6):1525-1539.e17. doi: 10.1016/j.cell.2016.11.005.
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YAP/TAZ at the Roots of Cancer.YAP/TAZ与癌症根源
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