A Phenome-Wide Association Study Uncovers a Role for Autoimmunity in the Development of Chronic Obstructive Pulmonary Disease.
作者信息
Ji Xiangming, Niu Xinnan, Qian Jun, Martucci Victoria, Pendergrass Sarah A, Gorlov Ivan P, Amos Christopher I, Denny Joshua C, Massion Pierre P, Aldrich Melinda C
机构信息
2 Georgia State University Atlanta, Georgia.
1 Vanderbilt University Medical Center Nashville, Tennessee.
出版信息
Am J Respir Cell Mol Biol. 2018 Jun;58(6):777-779. doi: 10.1165/rcmb.2017-0409LE.
Abstract
摘要
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本文引用的文献
1
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Nat Rev Genet. 2016 Mar;17(3):129-45. doi: 10.1038/nrg.2015.36. Epub 2016 Feb 15.
2
Autoreactivity to glucose regulated protein 78 links emphysema and osteoporosis in smokers.对葡萄糖调节蛋白78的自身反应性将吸烟者的肺气肿和骨质疏松症联系起来。
PLoS One. 2014 Sep 12;9(9):e105066. doi: 10.1371/journal.pone.0105066. eCollection 2014.
3
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations.NHGRI GWAS Catalog，一个经过精心策划的 SNP 与特征关联资源。
Nucleic Acids Res. 2014 Jan;42(Database issue):D1001-6. doi: 10.1093/nar/gkt1229. Epub 2013 Dec 6.
4
Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data.系统比较电子病历数据的表型全基因组关联研究和全基因组关联研究数据。
Nat Biotechnol. 2013 Dec;31(12):1102-10. doi: 10.1038/nbt.2749.
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Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):6961-6. doi: 10.1073/pnas.1304498110. Epub 2013 Apr 8.
6
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Am J Respir Crit Care Med. 2012 Dec 15;186(12):1238-47. doi: 10.1164/rccm.201206-1013OC. Epub 2012 Nov 9.
7
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