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在巴西儿科重症监护病房中,哪些儿童在 1 年内反复入院?

Which children account for repeated admissions within 1 year in a Brazilian pediatric intensive care unit?

机构信息

Hospital do Servidor Público Municipal, Departamento de Pediatria, Unidade de Terapia Intensiva Pediátrica, São Paulo, SP, Brazil.

Universidade Federal de São Paulo (UNIFESP), Unidade de Avaliação de Tecnologia em Saúde, São Paulo, SP, Brazil.

出版信息

J Pediatr (Rio J). 2019 Sep-Oct;95(5):559-566. doi: 10.1016/j.jped.2018.04.009. Epub 2018 May 30.

Abstract

OBJECTIVE

While studies have focused on early readmissions or readmissions during the same hospitalization in a pediatric intensive care unit, little is known about the children with recurrent admissions. We sought to assess the characteristics of patients readmitted within 1 year in a Brazilian pediatric intensive care unit.

METHODS

This was a retrospective study carried out in a tertiary pediatric intensive care unit. The outcome was the maximum number of readmissions experienced by each child within any 365-day interval during a 5-year follow-up period.

RESULTS

Of the 758 total eligible admissions, 75 patients (9.8%) were readmissions. Those patients accounted for 33% of all pediatric intensive care unit bed care days. Median time to readmission was 73 days for all readmissions. Logistic regression showed that complex chronic conditions (odds ratio 1.07), severe to moderate cognitive disability (odds ratio 1.08), and use of technology assistance (odds ratio 1.17) were associated with readmissions. Multiple admissions had a significantly prolonged duration of mechanical ventilation (8 vs. 6 days), longer length of pediatric intensive care unit (7 vs 4 days) and hospital stays (20 vs 9 days), and higher mortality rate (21.3% vs 5.1%) compared with index admissions.

CONCLUSION

The rate of pediatric intensive care unit readmissions within 1 year was low; however, it was associated with a relevant number of bed care days and worse outcomes. A 30-day index of readmission may be inadequate to mirror the burden of pediatric intensive care unit readmissions. Patients with complex chronic conditions, poor functional status or technology assistance are at higher risk for readmissions. Future studies should address the impact of qualitative interventions on healthcare and recurrent admissions.

摘要

目的

虽然已有研究集中于儿科重症监护病房(PICU)内的早期再入院或同一住院期间的再入院,但对于反复入院的患儿知之甚少。我们旨在评估巴西儿科重症监护病房内 1 年内再入院患者的特征。

方法

这是一项在三级儿科重症监护病房进行的回顾性研究。结局为在 5 年随访期间任何 365 天间隔内每个患儿经历的再入院次数的最大值。

结果

在 758 例符合条件的总入院人数中,有 75 例(9.8%)患儿发生再入院。这些患儿占儿科重症监护病房全部床位使用日的 33%。所有再入院的中位再入院时间为 73 天。Logistic 回归显示,复杂的慢性疾病(比值比 1.07)、严重至中度认知障碍(比值比 1.08)和使用技术辅助(比值比 1.17)与再入院相关。与首次入院相比,多次入院的患儿机械通气时间明显延长(8 天比 6 天)、儿科重症监护病房和住院时间延长(7 天比 4 天,20 天比 9 天),死亡率更高(21.3%比 5.1%)。

结论

PICU 内 1 年内的再入院率较低;然而,这与相当数量的床位使用日和较差的结局相关。30 天的再入院指数可能不足以反映 PICU 再入院的负担。具有复杂慢性疾病、功能状态较差或需要技术辅助的患者再入院风险较高。未来的研究应关注定性干预对医疗保健和再入院的影响。

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