肉毒毒素治疗中枢性神经病理性疼痛
Botulinum Toxin for Central Neuropathic Pain.
机构信息
Department of Rehabilitation Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul 06591, Korea.
Department of Rehabilitation Medicine, St. Paul's Hospital, College of Medicine, The Catholic University of Korea, Wangsan-ro 180, Dongdaemoon-Gu, Seoul 02559, Korea.
出版信息
Toxins (Basel). 2018 Jun 1;10(6):224. doi: 10.3390/toxins10060224.
Botulinum toxin (BTX) is widely used to treat muscle spasticity by acting on motor neurons. Recently, studies of the effects of BTX on sensory nerves have been reported and several studies have been conducted to evaluate its effects on peripheral and central neuropathic pain. Central neuropathic pain includes spinal cord injury-related neuropathic pain, post-stroke shoulder pain, multiple sclerosis-related pain, and complex regional pain syndrome. This article reviews the mechanism of central neuropathic pain and assesses the effect of BTX on central neuropathic pain.
肉毒毒素（BTX）通过作用于运动神经元而被广泛用于治疗肌肉痉挛。最近，关于 BTX 对感觉神经影响的研究已经有报道，并且已经进行了几项研究来评估其对周围和中枢神经性疼痛的作用。中枢神经性疼痛包括与脊髓损伤相关的神经性疼痛、中风后肩部疼痛、多发性硬化症相关的疼痛和复杂性区域疼痛综合征。本文综述了中枢神经性疼痛的机制，并评估了 BTX 对中枢神经性疼痛的作用。
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