Finkelman R D, Butler W T
J Oral Pathol. 1985 Mar;14(3):191-215. doi: 10.1111/j.1600-0714.1985.tb00483.x.
It is now accepted that vitamin D is an integral part of a complex endocrine system, one with far-reaching implications in mineral metabolism. Reviews of the sources, functions and metabolism of vitamin D, as currently understood, are presented as a prelude to discussions of the role of vitamin D in calcium and phosphorous homeostatis and possible specific roles for vitamin D in mineralized tissues. Data describing a possible regulatory function for vitamin D in bone and bone protein metabolism are presented. Some of the controversy which presently exists regarding the biochemical mechanism of the action of this vitamin is discussed. Finally, the possible relationship of vitamin D and disorders of skeletal tissues is described.
现在人们已经认识到，维生素D是复杂内分泌系统中不可或缺的一部分，该系统在矿物质代谢方面具有深远影响。作为讨论维生素D在钙和磷稳态中的作用以及维生素D在矿化组织中可能的特定作用的前奏，本文介绍了目前所了解的维生素D的来源、功能和代谢情况。文中还给出了描述维生素D在骨骼和骨蛋白代谢中可能具有调节功能的数据。讨论了目前关于这种维生素作用的生化机制存在的一些争议。最后，描述了维生素D与骨骼组织疾病之间可能的关系。
