Wang Xiao-Mei, Gong Jing, Li Si-Cong, Han Mei
Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Evid Based Complement Alternat Med. 2018 May 14;2018:2072091. doi: 10.1155/2018/2072091. eCollection 2018.
To compare the effectiveness and safety of acupuncture versus intramuscular injection of neostigmine.
Databases including CNKI, VIP, WanFang, SinoMed, PubMed, Cochrane Library, and clinicaltrials.gov database were retrieved for relevant literature, with the retrieval deadline being November 2017. Two reviewers independently screened, selected, and extracted data and validated the results. The methodological quality was evaluated with the "Risk of Bias" tool, and the meta-analysis was performed by using the RevMan 5.3.5 software.
Totally 953 patients with postpartum urinary retention from 15 randomized controlled trials entered the meta-analysis. 12 articles compared the clinical cure rate of acupuncture alone versus intramuscular injection of neostigmine and found the cure rate in the acupuncture group was 2 times that in the neostigmine group (RR, 1.91; 95% CI: 1.66-2.19). 15 articles compared the clinical effectiveness rate of acupuncture alone with that of intramuscular injection of neostigmine and found the clinical effectiveness rate was 28% higher in the acupuncture group than in the neostigmine group (RR: 1.28; 95% CI: 1.16-1.42). No adverse event was reported in the acupuncture group.
Acupuncture alone is more effective in treating postpartum urinary retention than intramuscular injection of neostigmine, with good safety profile. Therefore, it is a feasible and valuable technique in clinical settings.
比较针刺与新斯的明肌肉注射的有效性和安全性。
检索包括中国知网、维普、万方、中国生物医学文献数据库、PubMed、考克兰图书馆和clinicaltrials.gov数据库在内的数据库以获取相关文献,检索截止日期为2017年11月。两名评价员独立进行筛选、选择和数据提取并验证结果。采用“偏倚风险”工具评估方法学质量,并使用RevMan 5.3.5软件进行荟萃分析。
共有来自15项随机对照试验的953例产后尿潴留患者纳入荟萃分析。12篇文章比较了单纯针刺与新斯的明肌肉注射的临床治愈率,发现针刺组的治愈率是新斯的明组的2倍(RR = 1.91;95%CI:1.66 - 2.19)。15篇文章比较了单纯针刺与新斯的明肌肉注射的临床有效率,发现针刺组的临床有效率比新斯的明组高28%(RR = 1.28;95%CI:1.16 - 1.42)。针刺组未报告不良事件。
单纯针刺治疗产后尿潴留比新斯的明肌肉注射更有效,且安全性良好。因此,它是一种在临床环境中可行且有价值的技术。