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心理治疗联合药物治疗Ⅲ型慢性前列腺炎/慢性盆腔疼痛综合征患者:一项随机对照试验。

Psychotherapy combined with drug therapy in patients with category III chronic prostatitis/chronic pelvic pain syndrome: A randomized controlled trial.

作者信息

Wang Jianxin, Liang Kuixiang, Sun Huijing, Li Lianpeng, Wang Hongcai, Cao Jingyuan

机构信息

Department of Urology, Taizhou First People's Hospital, Taizhou, China.

Department of Urology, Binzhou Medical University Hospital, Binzhou, China.

出版信息

Int J Urol. 2018 Aug;25(8):710-715. doi: 10.1111/iju.13706. Epub 2018 Jun 3.

DOI:10.1111/iju.13706
PMID:29862568
Abstract

OBJECTIVES

To explore the efficacy of psychotherapy combined with drug therapy in patients with category III chronic prostatitis/chronic pelvic pain syndrome.

METHODS

A total of 156 patients with category III chronic prostatitis/chronic pelvic pain syndrome were randomly divided into two groups: the control group of 78 patients receiving routine medication; and the intervention group of 78 patients receiving psychological intervention therapy combined with routine medications. Treatment courses were for 3 months. The end-points were the response rate of the National Institutes of Health Chronic Prostatitis Symptom Index, International Index of Erectile Function-5, Self-Rating Anxiety Scale, Self-Rating Depression Scale and expressed prostatic secretion-white blood cells.

RESULTS

After 3 months, the average scores of the National Institutes of Health Chronic Prostatitis Symptom Index decreased to 10.1 ± 5.0 in the control group compared with 14.1 ± 4.9 in the intervention group; thus, significant differences were observed between the two groups in the study (P < 0.001). The average scores of the International Index of Erectile Function-5 were improved in the two groups, but compared with the control group, a more marked improvement was detected in the psychological intervention group, and there was a significant difference between the two groups (P < 0.001). There was significant difference between the two groups in terms of the Self-Rating Anxiety Scale and Self-Rating Depression Scale scores (P < 0.001). Expressed prostatic secretion-white blood cell counts significantly decreased to 4.4 ± 3.5 in the control group compared with 9.8 ± 3.4 in the intervention group (P < 0.001).

CONCLUSIONS

Psychological intervention therapy can effectively improve the psychological status and sexual function in patients with category III chronic prostatitis/chronic pelvic pain syndrome than the routine medication.

摘要

目的

探讨心理治疗联合药物治疗对Ⅲ型慢性前列腺炎/慢性盆腔疼痛综合征患者的疗效。

方法

将156例Ⅲ型慢性前列腺炎/慢性盆腔疼痛综合征患者随机分为两组:对照组78例,接受常规药物治疗;干预组78例,接受心理干预治疗联合常规药物治疗。疗程为3个月。观察指标包括美国国立卫生研究院慢性前列腺炎症状指数、国际勃起功能指数-5、焦虑自评量表、抑郁自评量表的反应率以及前列腺液白细胞计数。

结果

3个月后,对照组美国国立卫生研究院慢性前列腺炎症状指数平均得分降至10.1±5.0,干预组为14.1±4.9;两组间差异有统计学意义(P<0.001)。两组国际勃起功能指数-5平均得分均有所改善,但与对照组相比,心理干预组改善更显著,两组间差异有统计学意义(P<0.001)。两组焦虑自评量表和抑郁自评量表得分差异有统计学意义(P<0.001)。对照组前列腺液白细胞计数显著降至4.4±3.5,干预组为9.8±3.4(P<0.001)。

结论

与常规药物治疗相比,心理干预治疗能有效改善Ⅲ型慢性前列腺炎/慢性盆腔疼痛综合征患者的心理状态和性功能。

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