Department of Urology, Qilu Hospital (Qing Dao), Shandong University, Qingdao, Shandong 266000, China.
Department of Urology, Zoucheng People's Hospital, Zoucheng, Shandong 273500, China.
Comput Math Methods Med. 2022 May 2;2022:9227032. doi: 10.1155/2022/9227032. eCollection 2022.
UPOINT clinical phenotype system was used to estimate the type III prostatitis patients. Put in the erectile dysfunction (ED) domain and analysis the ED domain's effect towards the UPOINT system.
A total of 126 patients with type III prostatitis were prospectively collected and classified in each domain of the UPOINT system, including urinary, psychosocial, organ-specific, infection, neurological/systemic, and tenderness. Symptom severity was measured using the national institutes of health chronic prostatitis symptom index (NIH-CPSI) and the international prostate symptom score (IPSS). The erectile function was evaluated using the international index of erectile function (IIEF-5). Mental state was evaluated using the Symptom Checklist 90 (SCL-90). The quality of life of patients was assessed by the Quality of Life scale (QoL).
The percentage of patients positive for each domain was 60.32%, 43.65%, 53.17%, 11.11%, 42.06%, and 33.33% for the urinary, psychosocial, organ-specific, infection, neurological/systemic, and tenderness, respectively. There were significant correlations between the number of positive UPOINT domains and total NIH-CPSI ( = 0.630, < 0.001) and IPSS ( = 0.429, < 0.001). Symptom duration was associated with a number of positive domains ( = 0.194, < 0.05). After adding an ED domain to establish a modified UPOINT system, the correlation between the number of positive domains and symptom severity was not improved (0.630 to 0.590, < 0.001). The percentage of the patients who suffered psychosocial problems was 43.65%.
In our cohort, the number of positive domains was correlated with symptom severity. Inclusion of the ED phenotype in the UPOINT phenotype classification system did not significantly enhance the association of positive presentation with symptom severity. Our findings presented do not support the utility of using ED as a stand-alone item in the UPOINT domain. Psychological problems should be considered when treating type III prostatitis patients.
采用 UPOINT 临床表型系统对 III 型前列腺炎患者进行分类。将勃起功能障碍（ED）纳入 ED 域，并分析 ED 域对 UPOINT 系统的影响。
前瞻性收集 126 例 III 型前列腺炎患者，按 UPOINT 系统的每个域进行分类，包括泌尿系统、心理社会、器官特异性、感染、神经/系统性和压痛。使用国立卫生研究院慢性前列腺炎症状指数（NIH-CPSI）和国际前列腺症状评分（IPSS）评估症状严重程度。使用国际勃起功能指数（IIEF-5）评估勃起功能。使用症状清单 90（SCL-90）评估精神状态。通过生活质量量表（QoL）评估患者的生活质量。
每个域阳性患者的百分比分别为泌尿系统 60.32%、心理社会 43.65%、器官特异性 53.17%、感染 11.11%、神经/系统性 42.06%和压痛 33.33%。阳性 UPOINT 域数与 NIH-CPSI 总分（ = 0.630，< 0.001）和 IPSS（ = 0.429，< 0.001）呈显著正相关。症状持续时间与阳性域数相关（ = 0.194，< 0.05）。在加入 ED 域建立改良 UPOINT 系统后，阳性域数与症状严重程度的相关性并未改善（0.630 至 0.590，< 0.001）。患有心理社会问题的患者比例为 43.65%。
在我们的队列中，阳性域数与症状严重程度相关。将 ED 表型纳入 UPOINT 表型分类系统并不能显著增强阳性表现与症状严重程度的相关性。我们的研究结果不支持将 ED 用作 UPOINT 域中独立项目的实用性。在治疗 III 型前列腺炎患者时应考虑心理问题。
