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迷幻剂与人格

Psychedelics and Personality.

机构信息

ICEERS Foundation (International Center for Ethnobotanical Education, Research and Services) , 08015 Barcelona , Spain.

Department of Neurosciences and Behavior, Ribeirão Preto Medical School , University of São Paulo , 3900 Ribeirão Preto , Brazil.

出版信息

ACS Chem Neurosci. 2018 Oct 17;9(10):2304-2306. doi: 10.1021/acschemneuro.8b00237. Epub 2018 Jun 4.

Abstract

In the past decade, an increasing number of clinical trials are reporting evidence that psychedelics or serotonergic hallucinogens (such as lysergic acid diethylamide, psilocybin, and ayahuasca/dimethyltryptamine) could be effective in the treatment of mood, anxiety, and substance use disorders. The mechanisms responsible for these effects are not fully understood but seem to involve changes in bran dynamics in areas rich in serotonergic 5-HT receptors and in personality. In the present text, we present a brief and critical overview of the current research in this field, pointing out both promises and limitations of these studies.

摘要

在过去的十年中,越来越多的临床试验报告表明,迷幻药或血清素致幻剂(如麦角酸二乙酰胺、裸盖菇素和卡瓦胡椒/二甲色胺)可能在治疗情绪、焦虑和物质使用障碍方面有效。这些效果的机制尚不完全清楚,但似乎涉及富含血清素 5-HT 受体的大脑区域的动力学变化和个性改变。在本文中,我们对该领域的当前研究进行了简要而批判性的概述,指出了这些研究的前景和局限性。

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