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脊柱手术后预防手术部位感染的 5 项对策的实证分析——一种实用方法及文献回顾。

An empiric analysis of 5 counter measures against surgical site infections following spine surgery-a pragmatic approach and review of the literature.

机构信息

Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.

Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.

出版信息

Spine J. 2019 Feb;19(2):267-275. doi: 10.1016/j.spinee.2018.05.043. Epub 2018 Jun 2.

Abstract

BACKGROUND CONTEXT

Surgical site infections (SSI) following spine surgery are debilitating complications to patients and costly to the healthcare system.

PURPOSE

Review the impact and cost effectiveness of 5 SSI prevention interventions on SSI rates in an orthopedic spine surgery practice at a major quaternary healthcare system over a 10-year period.

STUDY DESIGN

Retrospective observational study.

PATIENT SAMPLE

All of the surgical patients of the 5 spine surgeons in our department over a 10-year period were included in this study.

OUTCOME MEASURES

SSI rates per year, standardized infection ratios (SIR) for laminectomies and fusions during the most recent 3-year period, year of implementation, and frequency of use of the different interventions, cost of the techniques.

METHODS

The SSI prevention techniques described in this paper include application of intrawound vancomycin powder, wound irrigation with dilute betadine solution, preoperative chlorhexidine gluconate scrubs, preoperative screening with nasal swabbing, and decolonization of S. aureus, and perioperative antibiotic administration. Our institution's infection prevention and control data were analyzed for the yearly SSI rates for the orthopedic spine surgery department from 2006 to 2016. In addition, our orthopedic spine surgeons were polled to determine with what frequency and duration they have been using the different SSI prevention interventions.

RESULTS

SSI rates decreased from almost 6% per year the first year of observation to less than 2% per year in the final 6 years of this study. A SIR of less than 1.0 for each year was observed for laminectomies and fusions for the period from 2013 to 2016. All surgeons polled at our institution uniformly used perioperative antibiotics, Hibiclens scrub, and the nasal swab protocol since the implementation of these techniques. Some variability existed in the frequency and duration of betadine irrigation and application of vancomycin powder. A cost analysis demonstrated these methods to be nominal compared with the cost of treating a single SSI.

CONCLUSIONS

It is possible to reduce SSI rates in spine surgery with easy, safe, and cost-effective protocols, when implemented in a standardized manner.

摘要

背景

脊柱手术后的手术部位感染(SSI)对患者造成严重的并发症,并给医疗保健系统带来巨大的经济负担。

目的

回顾在一家大型四级医疗机构的骨科脊柱手术实践中,10 年来 5 种 SSI 预防干预措施对 SSI 发生率的影响和成本效益。

研究设计

回顾性观察性研究。

患者样本

本研究纳入了过去 10 年期间我科 5 位脊柱外科医生的所有手术患者。

结果测量

每年的 SSI 发生率、最近 3 年期间的椎板切除术和融合术的标准化感染率(SIR)、实施年份和不同干预措施的使用频率、技术成本。

方法

本文描述的 SSI 预防技术包括:应用伤口内万古霉素粉末、用稀释的洗必泰溶液冲洗伤口、术前氯己定葡萄糖酸盐刷洗、术前鼻拭子筛查和金黄色葡萄球菌去定植以及围手术期抗生素给药。分析了我院感染预防和控制数据,以了解 2006 年至 2016 年骨科脊柱外科的年度 SSI 发生率。此外,还对我们的骨科脊柱外科医生进行了调查,以确定他们使用不同的 SSI 预防干预措施的频率和持续时间。

结果

SSI 发生率从观察的第一年的近 6%降至本研究的最后 6 年的每年 2%以下。在 2013 年至 2016 年期间,每年的椎板切除术和融合术的 SIR 均低于 1.0。在我院进行调查的所有外科医生均自这些技术实施以来,一直统一使用围手术期抗生素、Hibiclens 刷洗和鼻拭子方案。在洗必泰冲洗和万古霉素粉末应用的频率和持续时间方面存在一些差异。成本分析表明,与治疗单个 SSI 的成本相比,这些方法的成本微不足道。

结论

当以标准化方式实施时,使用简单、安全且具有成本效益的方案可以降低脊柱手术的 SSI 发生率。

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