Günther R W, Klose K J, Rückert K, Beyer J, Kuhn F P, Klotter H J
Gastrointest Radiol. 1985;10(2):145-52. doi: 10.1007/BF01893089.
A total of 42 islet-cell tumors were examined between 1972 and 1984. Problems of localization were only encountered in 31 tumors less than 2 cm in diameter. Of 31 small tumors, 27 were correctly localized using a combined diagnostic approach: ultrasound was successful in 12/20 tumors, CT in 9/21, angiography in 20/31, intraarterial digital subtraction angiography in 1/2, and pancreatic venous sampling in 13/16. The smallest tumor found by ultrasound and CT was 7 mm in diameter. Intraoperative ultrasound demonstrated all 9 insulinomas examined. Currently, the most useful techniques for localizing small islet-cell tumors are ultrasound, CT, and angiography. CT is particularly useful for tumor staging. Improvement of non-invasive diagnostic techniques will obviate the need for transhepatic blood sampling.
1972年至1984年间共检查了42例胰岛细胞瘤。定位问题仅在31例直径小于2厘米的肿瘤中出现。在31例小肿瘤中，27例通过联合诊断方法正确定位：超声在20例肿瘤中的12例成功定位，CT在21例中的9例成功定位，血管造影在31例中的20例成功定位，动脉内数字减影血管造影在2例中的1例成功定位，胰腺静脉采样在16例中的13例成功定位。超声和CT发现的最小肿瘤直径为7毫米。术中超声显示所检查的9例胰岛素瘤全部被发现。目前，定位小胰岛细胞瘤最有用的技术是超声、CT和血管造影。CT对肿瘤分期特别有用。非侵入性诊断技术的改进将不再需要经肝采血。
