Vio A, Barbanti F, Dell'Amore D, Amadori D, Ravaioli A, Maltoni M, Casadei Giunchi D
Ital J Surg Sci. 1985;15(1):51-5.
A series of 98 patients with spontaneous nipple discharge, is reported. Diagnosis was based on: clinical examination, cytology of breast secretion, mammography and galactography. Surgical resection was recommended in the following cases: galactographic evidence of intraductal papilloma or papillomatosis, dubious or positive cytology, persisting hemorrhagic or sero-hemorrhagic secretion. The injection of vital staining before the operation allowed the precise location of the lesion. In the group of patients studied ten cases of ductal carcinomas (5 in situ and 5 smaller than 1 cm), 4 cases of atypical intraductal hyperplasia, 13 cases of solitary papilloma and 22 cases of multiple papillomatosis were diagnosed.
本文报告了98例乳头自然溢液患者的情况。诊断依据包括：临床检查、乳腺分泌物细胞学检查、乳房X线摄影及乳管造影。在以下情况建议进行手术切除：乳管造影显示导管内乳头状瘤或乳头状瘤病、细胞学检查可疑或阳性、持续性出血或血清-血性溢液。术前注射活性染料可精确确定病变位置。在所研究的患者组中，诊断出10例导管癌（5例原位癌和5例小于1厘米）、4例非典型导管内增生、13例孤立性乳头状瘤和22例多发性乳头状瘤病。
