原发性中枢神经系统淋巴瘤之前富含B细胞的非肿瘤性前哨病变。
B cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma.
作者信息
Javier Rodrigo, Shaikh Nawal, Lesniak Maciej S, Sonabend Adam, Stupp Roger, Behdad Amir, Horbinski Craig
机构信息
Departments of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Tarry 2-705, 300 East Superior Street, Chicago, IL, 60611, USA.
Departments of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
出版信息
Diagn Pathol. 2018 Jun 5;13(1):37. doi: 10.1186/s13000-018-0717-9.
Primary central nervous system lymphoma (PCNSL) is an uncommon tumor in the brain. Although most PCNSL are readily diagnosed as diffuse large B cell lymphoma (DLBCL) on the first biopsy, very rare cases have been described in which the first detected intracerebral lesions are non-neoplastic, and are composed mostly of perivascular T cells, not B cells. This phenomenon is known as "sentinel lesions."
原发性中枢神经系统淋巴瘤（PCNSL）是一种脑部罕见肿瘤。尽管大多数PCNSL在首次活检时很容易被诊断为弥漫性大B细胞淋巴瘤（DLBCL），但已有非常罕见的病例报道，其中首次检测到的脑内病变是非肿瘤性的，主要由血管周围T细胞而非B细胞组成。这种现象被称为“前哨病变”。
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