Uchino K, Ogawara H, Akiyama T, Fukuchi A, Shibata S, Takahashi K, Narui T
J Antibiot (Tokyo). 1985 Feb;38(2):157-60. doi: 10.7164/antibiotics.38.157.
A novel 5'-nucleotidase inhibitor, named nucleoticidin, was isolated from a fermentation broth of Pseudomonas sp. The molecular weight was estimated by gel filtration to be over 1,000,000. Nucleoticidin is composed of D-glucose and D-mannose at a molar ratio of 1.7 to 1.0. Combined analyses using chemical and physico-chemical methods, such as gas liquid chromatography and mass fragmentography, revealed that nucleoticidin has a structural unit with mannosyl residues at the terminal of a (1----4) linked D-glucosyl main chain with beta-configuration.
一种名为核苷酸杀菌素的新型5'-核苷酸酶抑制剂，是从假单胞菌属的发酵液中分离出来的。通过凝胶过滤法估计其分子量超过1,000,000。核苷酸杀菌素由D-葡萄糖和D-甘露糖以1.7比1.0的摩尔比组成。使用化学和物理化学方法（如气相色谱法和质量碎片分析法）进行的联合分析表明，核苷酸杀菌素具有一个结构单元，在β构型的(1→4)连接的D-葡糖基主链末端带有甘露糖基残基。
