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血友病儿童的头部创伤及儿科急诊处理:描述性研究。

Head trauma in the haemophilic child and management in a paediatric emergency department: Descriptive study.

机构信息

Paediatric Emergency Department and Hematology Department, La Paz University Hospital, Madrid, Spain.

出版信息

Haemophilia. 2018 Jul;24(4):e187-e193. doi: 10.1111/hae.13526. Epub 2018 Jun 6.

Abstract

INTRODUCTION

Haemophilia is one of the most common inherited bleeding disorders in the Emergency Department (ED). The most dangerous site of bleeding is the central nervous system.

AIMS

To describe the characteristics of haemophiliacs arrived to our ED following a head trauma and to analyse the incidence of intracranial haemorrhage (ICH).

MATERIALS AND METHODS

Retrospective, analytical, observational study, conducted in a Paediatric ED. We included haemophilic patients aged from birth to 16 years who consulted after a head trauma over a 6-year period. Data collected included age, type of haemophilia and head trauma, symptoms, prophylaxis status, CT imaging, treatment and number of visits to the ED.

RESULTS

About 46 males and 85 episodes were analysed. The median age was 2.38 years. Severe haemophilia A was the most frequent type of disease (50%). All head injuries were mild, and the most frequent mechanism was a collision with an object (38.8%). In 62 episodes (72.9%) the patients were asymptomatic. The rest 23 events had symptomatology, being the most common headache (26%), emesis (21.7%) and drowsiness (17.4%). Head CT was obtained in 31 episodes, founding altered results in 10 (6 of them corresponding to ICH). All the patients with ICH had symptomatology. About 37 episodes required admission.

CONCLUSION

Intracranial haemorrhage is one of the most dangerous events in haemophiliacs and it may occur after a head trauma. Our study suggests that, in case of head trauma, CT must be obtained in symptomatic patients and in those with additional risk factors. Asymptomatic patients must have prolonged observation.

摘要

简介

血友病是急诊科(ED)最常见的遗传性出血性疾病之一。最危险的出血部位是中枢神经系统。

目的

描述因头部外伤就诊于我们急诊科的血友病患者的特征,并分析颅内出血(ICH)的发生率。

材料和方法

这是一项在儿科 ED 进行的回顾性、分析性、观察性研究。我们纳入了在 6 年期间因头部外伤就诊的年龄从出生到 16 岁的血友病患者。收集的数据包括年龄、血友病类型和头部外伤、症状、预防治疗情况、CT 成像、治疗和急诊科就诊次数。

结果

共分析了 46 名男性和 85 例病例。中位年龄为 2.38 岁。重型血友病 A 是最常见的疾病类型(50%)。所有头部损伤均为轻度,最常见的机制是与物体碰撞(38.8%)。62 例(72.9%)患者无症状。其余 23 例有症状,最常见的症状是头痛(26%)、呕吐(21.7%)和嗜睡(17.4%)。31 例进行了头部 CT 检查,发现 10 例(ICH 有 6 例)结果异常。所有 ICH 患者均有症状。约 37 例需要住院治疗。

结论

ICH 是血友病患者最危险的事件之一,可能在头部外伤后发生。我们的研究表明,对于头部外伤,有症状的患者和有其他危险因素的患者都需要进行 CT 检查。无症状患者必须进行长时间的观察。

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