Someya Takao, Sano Katsura, Hara Kotaro, Sagane Yoshimasa, Watanabe Toshihiro, Wijesekara R G S
ALBION Co. Ltd., 1-7-10 Ginza, Chuo-ku, Tokyo 104-0061, Japan.
Department of food and Cosmetic Science, Faculty of Bioindustry, Tokyo University of Agriculture, 196 Yasaka, Abashiri, Hokkaido 099-2493, Japan.
Data Brief. 2018 Jan 4;17:24-46. doi: 10.1016/j.dib.2017.12.055. eCollection 2018 Apr.
This data article provides gene expression profiles, determined by using real-time PCR, of fibroblasts and keratinocytes treated with 0.01% and 0.001% extracts of holy basil plant (), sri lankan local name "maduruthala", 0.1% and 0.01% extracts of malabar nut plant (), sri lankan local name "adayhoda" and 0.003% and 0.001% extracts of emblic myrobalan plant (), sri lankan local name "nelli", harvested in Sri Lanka. For fibroblasts, the dataset includes expression profiles for genes encoding hyaluronan synthase 1 (HAS1), hyaluronan synthase 2 (HAS2), hyaluronidase-1 (HYAL1), hyaluronidase-2 (HYAL2), versican, aggrecan, CD44, collagen, type I, alpha 1 (COL1A1), collagen, type III, alpha 1 (COL3A1), collagen, type VII, alpha 1 (COL7A1), matrix metalloproteinase 1 (MMP1), acid ceramidase, basic fibroblast growth factor (bFGF), fibroblast growth factor-7 (FGF7), vascular endothelial growth factor (VEGF), interleukin-1 alpha (IL-1α), cyclooxygenase-2 (cox2), transforming growth factor beta (TGF-β), and aquaporin 3 (AQP3). For keratinocytes, the expression profiles are for genes encoding HAS1, HAS2, HYAL1, HYAL2, versican, CD44, IL-1α, cox2, TGF-β, AQP3, Laminin5, collagen, type XVII, alpha 1 (COL17A1), integrin alpha-6 (ITGA6), ceramide synthase 3 (CERS3), elongation of very long chain fatty acids protein 1 (ELOVL1), elongation of very long chain fatty acids protein 4 (ELOVL4), filaggrin (FLG), transglutaminase 1 (TGM1), and keratin 1 (KRT1). The expression profiles are provided as bar graphs.
本文提供了使用实时聚合酶链反应（PCR）测定的基因表达谱，这些基因表达谱来自于用0.01%和0.001%的圣罗勒植物提取物（斯里兰卡当地名称为“maduruthala”）、0.1%和0.01%的马拉巴栗植物提取物（斯里兰卡当地名称为“adayhoda”）以及0.003%和0.001%的余甘子植物提取物（斯里兰卡当地名称为“nelli”）处理的成纤维细胞和角质形成细胞，这些植物均采自斯里兰卡。对于成纤维细胞，数据集包括编码透明质酸合酶1（HAS1）、透明质酸合酶2（HAS2）、透明质酸酶-1（HYAL1）、透明质酸酶-2（HYAL2）、多功能蛋白聚糖、聚集蛋白聚糖、CD44、I型胶原蛋白α1链（COL1A1）、III型胶原蛋白α1链（COL3A1）、VII型胶原蛋白α1链（COL7A1）、基质金属蛋白酶1（MMP1）、酸性神经酰胺酶、碱性成纤维细胞生长因子（bFGF）、成纤维细胞生长因子-7（FGF7）、血管内皮生长因子（VEGF）、白细胞介素-1α（IL-1α）、环氧化酶-2（cox2）、转化生长因子β（TGF-β）和水通道蛋白3（AQP3）的基因的表达谱。对于角质形成细胞，表达谱是关于编码HAS1、HAS2、HYAL1、HYAL2、多功能蛋白聚糖、CD44、IL-1α、cox2、TGF-β、AQP3、层粘连蛋白5、XVII型胶原蛋白α1链（COL17A1）、整合素α-6（ITGA6）、神经酰胺合酶3（CERS3）、超长链脂肪酸延伸蛋白1（ELOVL1）、超长链脂肪酸延伸蛋白4（ELOVL4）、丝聚合蛋白（FLG）、转谷氨酰胺酶1（TGM1）和角蛋白1（KRT1）的基因的。表达谱以柱状图形式呈现。
