Manokawinchoke Jeeranan, Nattasit Praphawi, Thongngam Tanutchaporn, Pavasant Prasit, Tompkins Kevin A, Egusa Hiroshi, Osathanon Thanaphum
Excellence Center in Regenerative Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand.
Department of Anatomy, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand.
Data Brief. 2018 Jan 31;17:407-413. doi: 10.1016/j.dib.2018.01.058. eCollection 2018 Apr.
Indirect immobilized ligand has been shown as an effective technique to activate Notch signalling The data presented in this article are related to the published article entitled "Indirect immobilized Jagged1 suppresses cell cycle progression and induces odonto/osteogenic differentiation in human dental pulp cells" (Manokawinchoke et al. 2017) [1]. This data article describes gene expression in indirect immobilized Jagged1 treated human dental pulp cells (hDPs) using high throughput RNA sequencing technique. These data are valuable to analyze the regulation of Notch signalling in hDPs for understanding its molecular mechanism(s). Raw RNA sequencing data were deposited in the NCBI Sequence Read Archive (SRP100068) and NCBI Gene Expression Omnibus (GSE94989).
间接固定配体已被证明是激活Notch信号传导的有效技术。本文所呈现的数据与已发表的题为“间接固定的Jagged1抑制人牙髓细胞的细胞周期进程并诱导牙本质/成骨分化”（Manokawinchoke等人，2017年）[1]的文章相关。本数据文章描述了使用高通量RNA测序技术在间接固定的Jagged1处理的人牙髓细胞（hDPs）中的基因表达。这些数据对于分析hDPs中Notch信号传导的调节以了解其分子机制很有价值。原始RNA测序数据已存入NCBI序列读取存档（SRP100068）和NCBI基因表达综合数据库（GSE94989）。
