Obe G, Palitti F, Tanzarella C, Degrassi F, De Salvia R
Mutat Res. 1985 Jun-Jul;150(1-2):359-68. doi: 10.1016/0027-5107(85)90133-2.
Restriction endonucleases (REs) are able to induce chromosomal aberrations in Chinese hamster ovary (CHO) cells. The G1 phase of the cell cycle seems to be especially sensitive for the induction of chromosomal aberrations by REs. The different capacities of REs to induce chromosomal aberrations are probably correlated with the number of recognition sites in the genome.
限制性内切酶(REs)能够在中国仓鼠卵巢(CHO)细胞中诱导染色体畸变。细胞周期的G1期似乎对REs诱导染色体畸变特别敏感。REs诱导染色体畸变的不同能力可能与基因组中的识别位点数量相关。