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前置性剖宫产预防性球囊内置于髂内动脉以预防凶险性前置胎盘产妇产后出血。

Pre-cesarean prophylactic balloon placement in the internal iliac artery to prevent postpartum hemorrhage among women with pernicious placenta previa.

机构信息

Department of Interventional Oncology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Department of Obstetrics and Gynecology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

出版信息

Int J Gynaecol Obstet. 2018 Sep;142(3):315-320. doi: 10.1002/ijgo.12559. Epub 2018 Jun 26.

DOI:10.1002/ijgo.12559
PMID:29876928
Abstract

OBJECTIVE

To evaluate pre-cesarean prophylactic balloon placement (PBP) in the internal iliac artery among women with pernicious placenta previa.

METHODS

The present retrospective study included women with pernicious placenta previa who underwent cesarean delivery at Shanghai Renji Hospital, Shanghai, China, between March 1, 2011, and June 30, 2017. Data were compared between patients who did and did not undergo PBP.

RESULTS

Among 42 patients included, 20 underwent PBP and 22 did not. Mean ± SD estimated blood loss was 2900.00 ± 2352.21 mL in the PBP group, and 4549.77 ± 2366.67 mL in the non-PBP group (P=0.025). The amount of transfused red blood cells was 8.40 ± 7.14 U and 13.00 ± 7.93 U (P=0.018), respectively. No patients in the PBP group developed postoperative disseminated intravascular coagulopathy, compared with 3 (14%) in the non-PBP group (P=0.087). In the PBP and non-PBP groups, the hospital stay duration was 7.40 ± 3.07 and 8.68 ± 2.58 days (P=0.029), and there were 1 and 7 patients who had obstetric hysterectomies (P=0.027), respectively. Two patients experienced PBP-related adverse events, including thrombosis and re-bleeding. There were no deaths.

CONCLUSION

Pre-cesarean PBP in the internal iliac artery was a safe and effective treatment that could reduce the incidence of both postpartum hemorrhage and hysterectomy among women with pernicious placenta previa.

摘要

目的

评估凶险性前置胎盘孕妇行剖宫产术前髂内动脉预防性球囊放置(PBP)的效果。

方法

本回顾性研究纳入 2011 年 3 月 1 日至 2017 年 6 月 30 日在上海交通大学医学院附属仁济医院行剖宫产术的凶险性前置胎盘孕妇。比较行 PBP 与未行 PBP 孕妇的临床结局。

结果

本研究共纳入 42 例孕妇,其中 20 例行 PBP,22 例未行 PBP。PBP 组的估计失血量为 2900.00±2352.21mL,而非 PBP 组为 4549.77±2366.67mL(P=0.025)。PBP 组与非 PBP 组的输血量分别为 8.40±7.14U 和 13.00±7.93U(P=0.018)。PBP 组无一例发生术后弥漫性血管内凝血,而非 PBP 组有 3 例(14%)(P=0.087)。PBP 组与非 PBP 组的住院时间分别为 7.40±3.07d 和 8.68±2.58d(P=0.029),行产科子宫切除术的患者分别有 1 例和 7 例(P=0.027)。2 例患者发生与 PBP 相关的不良事件,包括血栓形成和再出血。无死亡病例。

结论

剖宫产术前髂内动脉 PBP 是一种安全有效的治疗方法,可降低凶险性前置胎盘孕妇产后出血和子宫切除术的发生率。

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