Hubel D H, Livingstone M S
Nature. 1985;315(6017):325-7. doi: 10.1038/315325a0.
In primates, both the primary and secondary visual cortical areas can be subdivided histologically by staining for the mitochondrial enzyme cytochrome oxidase. In the primary visual cortex (area 17, the first cortical receiving area for visual information) these histological differences correspond to functional subdivisions, cytochrome-dark regions being concerned with information about colour and cytochrome-light regions concerned with form. Here we report that the second visual area, area 18, which receives its main cortical input from area 17 (refs 7,8), similarly has functional subdivisions that correspond to the cytochrome oxidase staining pattern. In area 18 the segregation between form and colour is maintained, reinforcing our notion that form and colour information follow parallel pathways. The specific differences between cells in areas 17 and 18 suggest that a possible step in hierarchical information processing is spatial generalization, analogous to the difference between simple and complex cells.
在灵长类动物中，初级和次级视觉皮层区域都可以通过对线粒体酶细胞色素氧化酶进行染色，从组织学上进行细分。在初级视觉皮层（17区，视觉信息的第一个皮层接收区域），这些组织学差异与功能细分相对应，细胞色素染色深的区域与颜色信息有关，而细胞色素染色浅的区域与形状信息有关。我们在此报告，第二视觉区，即18区，其主要皮层输入来自17区（参考文献7、8），同样具有与细胞色素氧化酶染色模式相对应的功能细分。在18区，形状和颜色之间的分离得以保持，这强化了我们关于形状和颜色信息遵循平行通路的观点。17区和18区细胞之间的具体差异表明，分层信息处理中一个可能的步骤是空间泛化，类似于简单细胞和复杂细胞之间的差异。
