孕期首诊妊娠合并单核细胞增生李斯特菌败血症成功治疗：1例报告及文献综述
Successful treatment of maternal listeria monocytogenes bacteremia in the first trimester of pregnancy: A case report and literature review.
作者信息
Chan Lai-Man, Lin Ho-Hsiung, Hsiao Sheng-Mou
机构信息
Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital, New Taipei, Taiwan.
Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital, New Taipei, Taiwan; Department of Obstetrics and Gynecology, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan.
出版信息
Taiwan J Obstet Gynecol. 2018 Jun;57(3):462-463. doi: 10.1016/j.tjog.2018.04.025.
OBJECTIVE
To report detailed clinical history and management of maternal listeria infection in the first trimester.
CASE REPORT
A 34-year-old woman at 11 gestational weeks was infected by Listeria monocytogenes with clinical symptoms of acute onset of a fever with subsequent headache and neck stiffness, and was treated with intravenous ampicillin at 2 g every 4 h for 3 weeks. A healthy, unaffected male baby was delivered at term. Histopathologic examination of the placenta did not reveal any chorioamnionitis, granulomas, microabscesses or vasculitis. The neonate developed well without any neurologic compromise at a six-week postnatal follow-up visit.
CONCLUSION
A favorable outcome of maternal listeria infection in the first trimester may be anticipated. Besides, intravenous ampicillin with or without gentamicin should be a reasonable treatment option for maternal listeria infection in the first trimester.
目的
报告孕早期孕妇李斯特菌感染的详细临床病史及治疗情况。
病例报告
一名34岁女性，孕11周时感染单核细胞增生李斯特菌，临床症状为急性发热起病，随后出现头痛和颈部僵硬，每4小时静脉注射2克氨苄西林治疗3周。足月分娩出一名健康、未受感染的男婴。胎盘组织病理学检查未发现任何绒毛膜羊膜炎、肉芽肿、微脓肿或血管炎。新生儿在出生后六周的随访中发育良好，无任何神经功能损害。
结论
孕早期孕妇李斯特菌感染可能预期有良好结局。此外，对于孕早期孕妇李斯特菌感染，静脉注射氨苄西林联合或不联合庆大霉素应是一种合理的治疗选择。
Zotero 插件