Maia Paulo Raphael Leite, Medeiros Ana Miryam C, Pereira Hallissa S G, Lima Kenio C, Oliveira Patrícia T
Department of Dentistry, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Department of Dentistry, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Aug;126(2):198-204. doi: 10.1016/j.oooo.2018.04.005. Epub 2018 Apr 24.
The aim of this study was to investigate the presence and associated factors of carotid artery calcification (CAC) in patients with chronic kidney disease (CKD) undergoing hemodialysis.
A total of 309 panoramic radiographs of patients with CKD (180 men and 129 women; mean age 43.7 years) undergoing hemodialysis were evaluated by a single radiologist to determine the frequency of CAC. An analysis of associated factors, such as age, sex, time spent in hemodialysis, arterial hypertension, diabetes mellitus, biochemical parameters, and other systemic diseases, was also performed.
The presence of CAC in patients with CKD, as determined on the basis of panoramic radiography, was 15.9%. The χ test revealed that there was a statistically significant association between certain factors, such as age, sex, and diabetes mellitus, and the presence of CAC (P < .05). Multivariate analysis demonstrated that time spent in hemodialysis was significantly associated with the occurrence of CAC.
A significant presence of CAC was detected on digital panoramic radiographs in patients with CKD undergoing hemodialysis. Calcification was more frequent in older patients, women, individuals with diabetes mellitus, and patients who had undergone hemodialysis for longer periods.
本研究旨在调查接受血液透析的慢性肾脏病（CKD）患者颈动脉钙化（CAC）的存在情况及相关因素。
由一名放射科医生对309例接受血液透析的CKD患者（180例男性和129例女性；平均年龄43.7岁）的全景X线片进行评估，以确定CAC的发生率。还对年龄、性别、血液透析时间、动脉高血压、糖尿病、生化参数和其他全身性疾病等相关因素进行了分析。
根据全景X线片确定，CKD患者中CAC的存在率为15.9%。χ检验显示，年龄、性别和糖尿病等某些因素与CAC的存在之间存在统计学上的显著关联（P < 0.05）。多变量分析表明，血液透析时间与CAC的发生显著相关。
在接受血液透析的CKD患者的数字全景X线片上检测到大量CAC。钙化在老年患者、女性、糖尿病患者以及血液透析时间较长的患者中更为常见。
