Fritsch E, Jakse G, Frommhold H
Rofo. 1985 Jun;142(6):654-8. doi: 10.1055/s-2008-1052732.
In a prospective study, 19 patients with advanced transitional carcinoma of the bladder (stages T.3 and T.4) were treated by combined radiotherapy and chemotherapy. A total of 450 mg cis-platinum or 1.6 mg/kg body weight were given in four treatment periods with three-week intervals. At the same time, the total dose of 60 Gy was given to the tumour over two periods (telecobalt or high-energy photons). There were few systemic or toxic side effects. Recurrence-free survival during the next 36 months was 76%, which compares with a control group treated by irradiation only, who had a survival of 48%.
在一项前瞻性研究中，19例晚期膀胱移行细胞癌（T3和T4期）患者接受了放疗和化疗联合治疗。在四个治疗周期中，每三周间隔给予总共450毫克顺铂或1.6毫克/千克体重。同时，在两个周期内给予肿瘤60戈瑞的总剂量（远距离钴治疗或高能光子治疗）。全身或毒性副作用很少。接下来36个月的无复发生存率为76%，而仅接受放疗的对照组生存率为48%。
