el Yousef S J, O'Connell D M, Duchesneau R H, Smith M J, Hubay C A, Guyton S P
AJR Am J Roentgenol. 1985 Jul;145(1):1-8. doi: 10.2214/ajr.145.1.1.
Thirty patients with suspected abnormality of the breasts on mammography were evaluated with magnetic resonance imaging (MRI) in a blind fashion. Spin-echo (SE) 250/30 msec scans were used to screen the examined breast. At the location of the suspected abnormality, inversion recovery (IR) 1000/30/300, SE 1000/30, and SE 1000/120 scans were performed. On the basis of these magnetic resonance images and experience with 70 previously studied patients, abnormalities of the breasts were grouped into five patterns. Ten malignant lesions exceeded 1 cm in diameter and were all correctly diagnosed by mammography and MRI. Of the remaining 20 benign conditions, four were suspicious for malignancy on MRI compared to eight with mammography. The shape of the lesion and the change in its signal intensity with different MR radiofrequency pulse sequences allows differentiation between a benign and a malignant process. On the basis of this preliminary experience, it seems MRI may have an adjunctive role to screening mammography. SE 1000/120 scans show higher signal intensity from carcinoma than from normal duct tissue, fibrocystic disease, and fibroadenoma. In this respect, it may allow some tissue specification in the breast.
对30例乳房X线摄影怀疑有异常的患者进行了磁共振成像（MRI）的盲法评估。采用自旋回波（SE）250/30毫秒扫描对受检乳房进行筛查。在怀疑异常的部位，进行了反转恢复（IR）1000/30/300、SE 1000/30和SE 1000/120扫描。根据这些磁共振图像以及对70例先前研究患者的经验，乳房异常被分为五种类型。10个直径超过1厘米的恶性病变均被乳房X线摄影和MRI正确诊断。在其余20例良性病变中，与乳房X线摄影诊断为可疑恶性的8例相比，MRI诊断为可疑恶性的有4例。病变的形状及其在不同MR射频脉冲序列下信号强度的变化有助于区分良性和恶性病变。基于这一初步经验，MRI似乎可能在乳房X线摄影筛查中起到辅助作用。SE 1000/120扫描显示癌灶的信号强度高于正常导管组织、纤维囊性疾病和纤维腺瘤。在这方面，它可能有助于对乳房内的一些组织进行鉴别。
