Nock B, Johnson A E, Feder H H, McEwen B S
Brain Res. 1985 Jun 10;336(1):148-52. doi: 10.1016/0006-8993(85)90426-3.
Tritium-sensitive film autoradiography was used to determine the distribution of alpha2-noradrenergic receptors (i.e. [3H]p-aminoclonidine binding sites) in guinea pig forebrain. Alpha 2-Receptors are heterogeneously distributed throughout the forebrain. Many limbic system structures, such as bed nucleus of stria terminalis, medial preoptic area, medial amygdaloid nucleus and lacunosum molecular layer in hippocampus were heavily labeled. We did not quantify receptor density in areas containing principally white matter but the optical density in those areas was similar to film background suggesting a very low receptor density. Low receptor concentrations were also found in areas that do not contain a high percentage of white matter, such as lateral septum and ventromedial hypothalamic nucleus.
用对氚敏感的胶片放射自显影法来确定豚鼠前脑α2 - 去甲肾上腺素能受体（即[3H] - 对氨基可乐定结合位点）的分布。α2受体在前脑呈不均匀分布。许多边缘系统结构，如终纹床核、内侧视前区、杏仁内侧核和海马分子层均有大量标记。我们没有对主要包含白质的区域的受体密度进行量化，但这些区域的光密度与胶片背景相似，表明受体密度非常低。在白质比例不高的区域，如外侧隔核和下丘脑腹内侧核，也发现了低受体浓度。
