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中颅窝入路切除前庭神经鞘瘤:十年经验。

Middle Fossa Approach for Resection of Vestibular Schwannomas: A Decade of Experience.

机构信息

Department of Neurosurgery, University of Cincinnati Medical Center, Cincinnati, Ohio.

Department of Otolaryngology Head and Neck Surgery, University of Cincinnati Medical Center, Cincinnati, Ohio.

出版信息

Oper Neurosurg (Hagerstown). 2019 Feb 1;16(2):147-158. doi: 10.1093/ons/opy126.

Abstract

BACKGROUND

The middle cranial fossa (MCF) approach is a challenging surgical technique for the resection of small and intermediate sized, primarily intracanalicular, vestibular schwannomas (VS), with the goal of hearing preservation (HP).

OBJECTIVE

To describe a decade-long, single institutional experience with the MCF approach for resection of VS.

METHODS

This is a retrospective cohort study of 63 patients who underwent the MCF approach for resection of VS from 2006 to 2016. Audiometric data included pure-tone average (PTA), low-tone pure-tone average (LtPTA), word recognition score, and American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) hearing classification at presentation and follow-up. Patients with postoperative serviceable (AAO-HNS class A-B) and/or useful (AAO-HNS class A-C) hearing were compared to those without HP. Facial nerve function was assessed using the House-Brackmann scale.

RESULTS

The mean age and duration of follow-up were 50 ± 13 yr and 21 ± 21 mo, respectively. The mean tumor size was 10 ± 4 mm. The serviceable and usable HP rates were 54% and 50%, respectively. Some residual hearing was preserved in 71% of patients. Large tumor size (P = .05), volume (P = .03), and extrameatal tumor extension (P = .03) were associated with poor audiometric outcomes. The presence of a fundal fluid cap (P = .01) was a favorable finding. At definitive testing, LtPTA was significantly better preserved than traditional PTA (P = .01). Facial nerve outcomes, tumor control rates, and durability of audiometric outcomes were excellent. 47% of patients pursued aural rehabilitation.

CONCLUSION

In our series, the MCF approach for VS provided excellent rates of tumor and facial nerve function, with durable serviceable HP.

摘要

背景

中颅窝(MCF)入路是切除小及中等大小、主要位于管内的前庭神经鞘瘤(VS)的一种具有挑战性的手术技术,其目标是保留听力(HP)。

目的

描述 MCF 入路切除 VS 的长达十年的单机构经验。

方法

这是一项回顾性队列研究,纳入了 2006 年至 2016 年间接受 MCF 入路切除 VS 的 63 例患者。听力数据包括纯音平均听阈(PTA)、低频纯音平均听阈(LtPTA)、言语识别得分和美国耳鼻喉科学院-头颈外科学会(AAO-HNS)听力分类,包括术前和随访时的分类。将术后具有可服务(AAO-HNS 分级 A-B)和/或有用(AAO-HNS 分级 A-C)听力的患者与无听力保留(HP)的患者进行比较。面神经功能采用 House-Brackmann 量表进行评估。

结果

患者的平均年龄和随访时间分别为 50±13 岁和 21±21 个月。肿瘤平均大小为 10±4mm。可服务和有用的 HP 率分别为 54%和 50%。71%的患者保留了一定的残余听力。较大的肿瘤大小(P=0.05)、体积(P=0.03)和外听道外肿瘤延伸(P=0.03)与较差的听力结果相关。存在颅底液帽(P=0.01)是一个有利的发现。在最终测试中,LtPTA 明显优于传统 PTA(P=0.01)。面神经功能结果、肿瘤控制率和听力结果的持久性均非常出色。47%的患者接受了听觉康复。

结论

在我们的系列研究中,MCF 入路治疗 VS 提供了极好的肿瘤和面神经功能保留率,具有持久的可服务性 HP。

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