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溃疡性结肠炎中一个被忽视的问题:肠系膜淋巴结

A Neglected Issue in Ulcerative Colitis: Mesenteric Lymph Nodes.

作者信息

Sahin Abdurrahman, Artas Hakan, Eroglu Yesim, Tunc Nurettin, Oguz Gulcan, Demirel Ulvi, Poyrazoglu Orhan Kursat, Yalniz Mehmet, Bahcecioglu Ibrahim Halil

机构信息

Division of Gastroenterology, Department of Internal Medicine, Firat University School of Medicine, 23119 Elazig, Turkey.

Department of Radiology, Firat University School of Medicine, 23119 Elazig, Turkey.

出版信息

J Clin Med. 2018 Jun 8;7(6):142. doi: 10.3390/jcm7060142.

Abstract

Data evaluating the presence and characteristics of mesenteric lymph nodes (LNs) in patients with ulcerative colitis (UC) are scarce. The aim of this study is to determine the presence and characteristics of LNs in UC. The LN characteristics in computed tomography (CT), including LN dimension and attenuation, were evaluated retrospectively in 100 patients with UC (61 active and 39 inactive cases). Clinical characteristics and laboratory parameters, including CBC, biochemical analysis, erythrocyte sedimentation rate (ESR), and C reactive protein (CRP) were also compared. Mesenteric LNs were evident in all patients with UC. The attenuation and dimension of mesenteric LNs did not differ between active and inactive patients with UC. No correlation was found among patients with UC in terms of LN dimension, attenuation, ESR, CRP, leucocyte, and albumin (all with > 0.05). The current study suggested that inflammation results in the development of mesenteric LN in UC, similar to Crohn’s disease and other inflammatory disorders.

摘要

评估溃疡性结肠炎(UC)患者肠系膜淋巴结(LN)的存在情况及特征的数据较少。本研究的目的是确定UC中LN的存在情况及特征。对100例UC患者(61例活动期和39例非活动期病例)的计算机断层扫描(CT)中LN特征(包括LN大小和衰减)进行回顾性评估。还比较了临床特征和实验室参数,包括全血细胞计数(CBC)、生化分析、红细胞沉降率(ESR)和C反应蛋白(CRP)。所有UC患者均可见肠系膜LN。活动期和非活动期UC患者的肠系膜LN衰减和大小无差异。在UC患者中,LN大小、衰减、ESR、CRP、白细胞和白蛋白之间均未发现相关性(所有P>0.05)。本研究表明,与克罗恩病和其他炎症性疾病相似,炎症导致UC中肠系膜LN的形成。

相似文献

本文引用的文献

1
Mesenteric organ lymphatics and inflammatory bowel disease.肠系膜器官淋巴管与炎症性肠病
Ann Anat. 2018 Jul;218:199-204. doi: 10.1016/j.aanat.2018.03.006. Epub 2018 Apr 30.
4
Lymphatic system: an active pathway for immune protection.淋巴系统:免疫保护的一条活跃途径。
Semin Cell Dev Biol. 2015 Feb;38:83-9. doi: 10.1016/j.semcdb.2014.11.012. Epub 2014 Dec 19.
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Radiographical evaluation of ulcerative colitis.溃疡性结肠炎的放射学评估。
Gastroenterol Rep (Oxf). 2014 Aug;2(3):169-77. doi: 10.1093/gastro/gou026. Epub 2014 May 19.
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Ulcerative colitis.溃疡性结肠炎。
Lancet. 2012 Nov 3;380(9853):1606-19. doi: 10.1016/S0140-6736(12)60150-0. Epub 2012 Aug 20.
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Aliment Pharmacol Ther. 2011 Sep;34(5):533-43. doi: 10.1111/j.1365-2036.2011.04759.x. Epub 2011 Jul 7.
10
Emerging roles of lymphatics in inflammatory bowel disease.淋巴管在炎症性肠病中的新作用。
Ann N Y Acad Sci. 2010 Oct;1207 Suppl 1:E75-85. doi: 10.1111/j.1749-6632.2010.05757.x.

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