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麻醉药物使用与全髋关节置换术

Narcotic use and total hip arthroplasty.

作者信息

Bolarinwa Surajudeen A, Casp Aaron A, Cancienne Jourdan M, Werner Brian C, Browne James A

机构信息

University of Virginia Health System, Charlottesville, VA, USA.

出版信息

Hip Int. 2019 Jul;29(4):379-384. doi: 10.1177/1120700018781759. Epub 2018 Jun 11.

Abstract

BACKGROUND

The purpose of this study is to: (1) characterise risk factors for prolonged narcotic use following total hip arthroplasty (THA); (2) examine preoperative and prolonged postoperative narcotic use as independent risk factors for complications following THA.

METHODS

A national database identified primary THA patients from 2007-2015. Preoperative (POU) and prolonged postoperative narcotics users (PPU) were identified. A multivariable logistic regression analysis was utilised to identify any patient-related risk factors for prolonged use, and examined POU and PPU as risk factors for complications following THA.

RESULTS

55,354 THA patients were included, 18,740 (33.8%) POU and 14,996 (27.1%) PPU. Preoperative narcotics use was the most significant factor associated with prolonged postoperative narcotic use. Preoperative and prolonged postoperative use were associated with significantly higher complications postoperatively.

CONCLUSIONS

Preoperative narcotic use is the most significant patient specific risk factor for prolonged postoperative narcotic use. POUs and PPUs are at a significantly higher risk of postoperative infection and revision surgery.

摘要

背景

本研究的目的是:(1)确定全髋关节置换术(THA)后长期使用麻醉剂的风险因素;(2)将术前和术后长期使用麻醉剂作为THA后并发症的独立风险因素进行研究。

方法

一个全国性数据库确定了2007年至2015年的初次THA患者。确定了术前使用麻醉剂者(POU)和术后长期使用麻醉剂者(PPU)。采用多变量逻辑回归分析来确定长期使用的任何患者相关风险因素,并将POU和PPU作为THA后并发症的风险因素进行研究。

结果

纳入了55354例THA患者,其中18740例(33.8%)为POU,14996例(27.1%)为PPU。术前使用麻醉剂是与术后长期使用麻醉剂相关的最显著因素。术前和术后长期使用与术后显著更高的并发症发生率相关。

结论

术前使用麻醉剂是术后长期使用麻醉剂最显著的患者特异性风险因素。POU和PPU术后感染和翻修手术的风险显著更高。

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